Technology Process of Propanedioic acid, (trans-4-carboxycyclohexyl)-, 1,3-diethyl ester
There total 5 articles about Propanedioic acid, (trans-4-carboxycyclohexyl)-, 1,3-diethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
ethanol;
at 20 ℃;
for 1h;
DOI:10.1021/jm010313k
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 95 percent / TiCl4; pyridine / tetrahydrofuran; CH2Cl2 / 10 h / 20 °C
2: 36 percent / hydrogen / Pd-C / ethanol / 1 h / 20 °C
With
pyridine; hydrogen; titanium tetrachloride;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1021/jm010313k
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 83 percent / PCC; neutral alumina / CHCl3 / 3 h
2: 95 percent / NaOH / methanol; H2O / 3 h
3: 95 percent / potassium carbonate / dimethylformamide / 3 h
4: 95 percent / TiCl4; pyridine / tetrahydrofuran; CH2Cl2 / 10 h / 20 °C
5: 36 percent / hydrogen / Pd-C / ethanol / 1 h / 20 °C
With
pyridine; aluminum oxide; sodium hydroxide; hydrogen; titanium tetrachloride; potassium carbonate; pyridinium chlorochromate;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; chloroform; water; N,N-dimethyl-formamide;
DOI:10.1021/jm010313k