1,2,4-Triazolo(4,3-a)pyrimidin-3(2H)-one, 5,6,7,8-tetrahydro-2-phenyl-

Base Information

Chemical Name:1,2,4-Triazolo(4,3-a)pyrimidin-3(2H)-one, 5,6,7,8-tetrahydro-2-phenyl-
CAS No.:105896-19-3
Molecular Formula:C₁₁H₁₂N₄O
Molecular Weight:216.242
Hs Code.:
DSSTox Substance ID:DTXSID00147409

Synonyms:5,6,7,8-Tetrahydro-2-phenyl-1,2,4-triazolo(4,3-a)pyrimidin-3(2H)-one;1,2,4-Triazolo(4,3-a)pyrimidin-3(2H)-one, 5,6,7,8-tetrahydro-2-phenyl-;105896-19-3;DTXSID00147409;LS-156854;2-phenyl-3-oxo-2,3,5,6,7,8-hexahydro-s-triazolo[4,3-a]pyrimidine

Suppliers and Price of 1,2,4-Triazolo(4,3-a)pyrimidin-3(2H)-one, 5,6,7,8-tetrahydro-2-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,2,4-Triazolo(4,3-a)pyrimidin-3(2H)-one, 5,6,7,8-tetrahydro-2-phenyl-

Chemical Property:

Vapor Pressure:0.00028mmHg at 25°C
Boiling Point:322.4°C at 760 mmHg
Flash Point:148.8°C
Density:1.41g/cm³
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:216.10111102
Heavy Atom Count:16
Complexity:322

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNC2=NN(C(=O)N2C1)C3=CC=CC=C3

Technology Process of 1,2,4-Triazolo(4,3-a)pyrimidin-3(2H)-one, 5,6,7,8-tetrahydro-2-phenyl-

There total 4 articles about 1,2,4-Triazolo(4,3-a)pyrimidin-3(2H)-one, 5,6,7,8-tetrahydro-2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 2-(N'-Phenyl-hydrazino)-5,6-dihydro-4H-pyrimidine-1-carboxylic acid ethyl ester; hydrochloride

: 105896-19-3
2-Phenyl-3-oxo-2,3,5,6,7,8-hexahydro-s-triazolo<4,3-a>pyrimidine

Guidance literature:: With potassium carbonate; for 1h;
DOI:10.3987/R-1986-01-0093

Reference yield: 70.0%

: 100-63-0
phenylhydrazine

: 54679-24-2
1-Ethoxycarbonyl-2-methylthio-1,4,5,6-tetrahydropyrimidine

: 105896-19-3
2-Phenyl-3-oxo-2,3,5,6,7,8-hexahydro-s-triazolo<4,3-a>pyrimidine

Guidance literature:: In ethanol; for 7h; Heating;
DOI:10.1007/BF00473485

Reference yield:

: 59-88-1
phenylhydrazine hydrochloride

: 105896-19-3
2-Phenyl-3-oxo-2,3,5,6,7,8-hexahydro-s-triazolo<4,3-a>pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / Heating

2: 82 percent / 20percent aq, K₂CO₃ / 1 h

With potassium carbonate;
DOI:10.3987/R-1986-01-0093