(2-((4-(Aminosulphonyl)phenyl)amino)-1,4-dihydro-4-oxo-5-pyrimidinyl)carbamoyl chloride

Base Information

Chemical Name:(2-((4-(Aminosulphonyl)phenyl)amino)-1,4-dihydro-4-oxo-5-pyrimidinyl)carbamoyl chloride
CAS No.:89074-09-9
Molecular Formula:C11H10 Cl N5 O4 S
Molecular Weight:343.75
Hs Code.:
European Community (EC) Number:289-467-1
DSSTox Substance ID:DTXSID30237529
Nikkaji Number:J348.569B
Wikidata:Q83119718
Mol file:89074-09-9.mol

Synonyms:EINECS 289-467-1;89074-09-9;(2-((4-(Aminosulphonyl)phenyl)amino)-1,4-dihydro-4-oxo-5-pyrimidinyl)carbamoyl chloride;[2-[[4-(aminosulphonyl)phenyl]amino]-1,4-dihydro-4-oxo-5-pyrimidinyl]carbamoyl chloride;C11H10ClN5O4S;DTXSID30237529;C11-H10-Cl-N5-O4-S;[[2-[[4-(Aminosulfonyl)phenyl]amino]-1,4-dihydro-4-oxopyrimidin]-5-yl]carbamic acid chloride

Suppliers and Price of (2-((4-(Aminosulphonyl)phenyl)amino)-1,4-dihydro-4-oxo-5-pyrimidinyl)carbamoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of (2-((4-(Aminosulphonyl)phenyl)amino)-1,4-dihydro-4-oxo-5-pyrimidinyl)carbamoyl chloride

Chemical Property:

PSA：159.17000
Density:1.78g/cm³
LogP:3.21160
XLogP3:-0.3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:343.0142027
Heavy Atom Count:22
Complexity:631

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1NC2=NC=C(C(=O)N2)NC(=O)Cl)S(=O)(=O)N

Technology Process of (2-((4-(Aminosulphonyl)phenyl)amino)-1,4-dihydro-4-oxo-5-pyrimidinyl)carbamoyl chloride

There total 2 articles about (2-((4-(Aminosulphonyl)phenyl)amino)-1,4-dihydro-4-oxo-5-pyrimidinyl)carbamoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 75-44-5
phosgene

: 77997-17-2
5-amino-2-(p-aminosulfonyl)anilino-4-hydroxy-pyrimidine

: 89074-09-9
2-(p-aminosulfonyl)anilino-5-chlorocarbonylamino-4-hydroxy-pyrimidine

Guidance literature:: In tetrahydrofuran; at 0 - 5 ℃; for 20h;

Reference yield:

: 97091-03-7
5-benzoylamino-2-(p-aminosulfonyl)anilino-4-hydroxy-pyrimidine

: 89074-09-9
2-(p-aminosulfonyl)anilino-5-chlorocarbonylamino-4-hydroxy-pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / 17.5percent NaOH / H₂O / 3 h / Heating

2: 96 percent / tetrahydrofuran / 20 h / 0 - 5 °C

With sodium hydroxide; In tetrahydrofuran; water;