Benzonitrile, 2,5-difluoro-4-[2-oxo-4-(trifluoromethyl)-1(2H)-pyridinyl]-

Base Information

Chemical Name:Benzonitrile, 2,5-difluoro-4-[2-oxo-4-(trifluoromethyl)-1(2H)-pyridinyl]-
CAS No.:390412-38-1
Molecular Formula:C13H5F5N2O
Molecular Weight:300.188
Hs Code.:
DSSTox Substance ID:DTXSID90457726
Wikidata:Q82280688
Mol file:390412-38-1.mol

Synonyms:Benzonitrile, 2,5-difluoro-4-[2-oxo-4-(trifluoromethyl)-1(2H)-pyridinyl]-;390412-38-1;SCHEMBL7698169;DTXSID90457726;CKYPMFVPDGEOFP-UHFFFAOYSA-N

Suppliers and Price of Benzonitrile, 2,5-difluoro-4-[2-oxo-4-(trifluoromethyl)-1(2H)-pyridinyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzonitrile, 2,5-difluoro-4-[2-oxo-4-(trifluoromethyl)-1(2H)-pyridinyl]-

Chemical Property:

PSA：45.79000
LogP:3.00618
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:300.03220360
Heavy Atom Count:21
Complexity:545

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CN(C(=O)C=C1C(F)(F)F)C2=C(C=C(C(=C2)F)C#N)F

Technology Process of Benzonitrile, 2,5-difluoro-4-[2-oxo-4-(trifluoromethyl)-1(2H)-pyridinyl]-

There total 1 articles about Benzonitrile, 2,5-difluoro-4-[2-oxo-4-(trifluoromethyl)-1(2H)-pyridinyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98349-22-5
2,4,5-trifluorobenzonitrile

: 50650-59-4
4-(trifluoromethyl)-2-pyridone

: 390412-38-1
2,5-difluoro-4-[2-oxo-4-(trifluoromethyl)-1-(2H)-pyridinyl]benzonitrile

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 - 80 ℃; for 13h;

Reference yield: 64.0%

: 390412-38-1
2,5-difluoro-4-[2-oxo-4-(trifluoromethyl)-1-(2H)-pyridinyl]benzonitrile

: 124-41-4
sodium methylate

: 390412-39-2
5-fluoro-2-methoxy-4-[2-oxo-4-(trifluoromethyl)-1-(2H)-pyridinyl]benzonitrile

Guidance literature:: In methanol; at 20 ℃;

Reference yield:

: 390412-38-1
2,5-difluoro-4-[2-oxo-4-(trifluoromethyl)-1-(2H)-pyridinyl]benzonitrile

: 107-19-7
propargyl alcohol

: 390412-40-5
5-fluoro-4-[2-oxo-4-(trifluoromethyl)-1-(2H)-pyrindinyl-2-(2-propinyloxy)]benzonitrile

Guidance literature:: propargyl alcohol; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 0.166667h;

2,5-difluoro-4-[2-oxo-4-(trifluoromethyl)-1-(2H)-pyridinyl]benzonitrile; In tetrahydrofuran; mineral oil; Heating / reflux;