(2-Amino-4,5-dimethoxyphenyl)(p-tolyl)methanone

Base Information

Chemical Name:(2-Amino-4,5-dimethoxyphenyl)(p-tolyl)methanone
CAS No.:391251-83-5
Molecular Formula:C16H17NO3
Molecular Weight:271.316
Hs Code.:
DSSTox Substance ID:DTXSID00428088
Wikidata:Q82240869
Mol file:391251-83-5.mol

Synonyms:(2-Amino-4,5-dimethoxyphenyl)(p-tolyl)methanone;391251-83-5;(2-Amino-4,5-dimethoxyphenyl)-p-tolylmethanone;(2-amino-4,5-dimethoxyphenyl)-(4-methylphenyl)methanone;(2-amino-4,5-dimethoxy-phenyl)-p-tolyl-methanone;MFCD06739582;DTXSID00428088;AKOS013745290;BS-17182;CS-0162346;D83551

Suppliers and Price of (2-Amino-4,5-dimethoxyphenyl)(p-tolyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (2-Amino-4,5-dimethoxyphenyl)(p-tolyl)methanone

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:271.12084340
Heavy Atom Count:20
Complexity:326

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(=O)C2=CC(=C(C=C2N)OC)OC

Technology Process of (2-Amino-4,5-dimethoxyphenyl)(p-tolyl)methanone

There total 4 articles about (2-Amino-4,5-dimethoxyphenyl)(p-tolyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 681470-02-0
(4,5-dimethoxy-2-nitrophenyl)-(4-methylphenyl)methanone

: 391251-83-5
(2-amino-4,5-dimethoxyphenyl)-(4-methylphenyl)methanone

Guidance literature:: With iron; acetic acid; In water; ethyl acetate; for 6h; Heating;
DOI:10.1016/j.tet.2006.10.056

Reference yield:

: 91-16-7
1,2-dimethoxybenzene

: 391251-83-5
(2-amino-4,5-dimethoxyphenyl)-(4-methylphenyl)methanone

Guidance literature:: Multi-step reaction with 3 steps

1: AlCl₃ / benzene / 2.5 h / 55 - 60 °C

2: 68 percent / HNO₃; AcOH / 0.5 h / 0 - 20 °C

3: 73 percent / Fe; AcOH / H₂O; ethyl acetate / 6 h / Heating

With aluminium trichloride; nitric acid; iron; acetic acid; In water; ethyl acetate; benzene; 1: Friedel-Crafts reaction;
DOI:10.1016/j.tet.2006.10.056

Reference yield:

: 874-60-2
4-methyl-benzoyl chloride

: 391251-83-5
(2-amino-4,5-dimethoxyphenyl)-(4-methylphenyl)methanone

Guidance literature:: Multi-step reaction with 3 steps

1: AlCl₃ / benzene / 2.5 h / 55 - 60 °C

2: 68 percent / HNO₃; AcOH / 0.5 h / 0 - 20 °C

3: 73 percent / Fe; AcOH / H₂O; ethyl acetate / 6 h / Heating

With aluminium trichloride; nitric acid; iron; acetic acid; In water; ethyl acetate; benzene; 1: Friedel-Crafts reaction;
DOI:10.1016/j.tet.2006.10.056