2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid

Base Information

Chemical Name:2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid
CAS No.:393509-22-3
Molecular Formula:C13H12FNO2
Molecular Weight:233.242
Hs Code.:2933990090
DSSTox Substance ID:DTXSID20582979
Mol file:393509-22-3.mol

Synonyms:393509-22-3;2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid;SCHEMBL5088953;DTXSID20582979;IDOLDTCRCJMHBH-UHFFFAOYSA-N;(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid;2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)aceticacid;(+-)-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid;(+/-)-(7-Fluoro-1, 2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid;(+/-)-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid

Suppliers and Price of 2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)aceticacid 95+%
1g
$ 772.00

Alichem
2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)aceticacid
1g
$ 615.44

Total 2 raw suppliers

Chemical Property of 2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid

Chemical Property:

Vapor Pressure:1.96E-09mmHg at 25°C
Boiling Point:464.7±40.0 °C(Predicted)
PKA:4.60±0.10(Predicted)
PSA：53.09000
Density:1.393±0.06 g/cm3(Predicted)
LogP:2.81150
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:233.08520679
Heavy Atom Count:17
Complexity:323

Purity/Quality:

≥99% ^*data from raw suppliers

2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)aceticacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C1CC(=O)O)NC3=C2C=C(C=C3)F

Technology Process of 2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid

There total 10 articles about 2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 393509-21-2
ethyl (7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetate

: 393509-22-3
(+/-) 2-(7-fluoro-1,2,3-trihydrocyclopenta[2,3-b]indol-3-yl)acetic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; methanol; at 60 ℃; for 0.25h;
DOI:10.1021/jm0603668

Reference yield:

: C₁₃H₁₄FNO₂

: 393509-22-3
(+/-) 2-(7-fluoro-1,2,3-trihydrocyclopenta[2,3-b]indol-3-yl)acetic acid

Guidance literature:: C₁₃H₁₄FNO₂; With tetrabutyl-ammonium chloride; potassium acetate; palladium diacetate; In ISOPROPYLAMIDE; at 115 ℃; for 5h;

With potassium hydroxide; In ISOPROPYLAMIDE; water; at 20 ℃; for 1h;

Reference yield:

: 571170-84-8
[2-(2-bromo-4-fluoro-phenylimino)-cyclopentyl]-acetic acid ethyl ester

: 393509-22-3
(+/-) 2-(7-fluoro-1,2,3-trihydrocyclopenta[2,3-b]indol-3-yl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 252 g / nBu₄NCl / Pd(OAc)2 / dimethylformamide / 1 h / 80 °C

2: 92 percent / aq. NaOH / tetrahydrofuran; methanol / 0.25 h / 60 °C

With sodium hydroxide; tetrabutyl-ammonium chloride; palladium diacetate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm0603668