4α-Methylcyclohexane-1β-methanol

Base Information

• Chemical Name: 4α-Methylcyclohexane-1β-methanol
• CAS No.: 3937-49-3
• Molecular Formula: C8H16O
• Molecular Weight: 128.214
• Mol file: 3937-49-3.mol

Synonyms:

Chemical Property of 4α-Methylcyclohexane-1β-methanol

Chemical Property:

• Boiling Point: 99-101 °C(Press: 23 Torr)
• PKA: 15.05±0.10(Predicted)
• PSA: 20.23000
• Density: 0.884±0.06 g/cm3(Predicted)
• LogP: 1.80500

Purity/Quality:

98%min ^*data from raw suppliers

(Trans-4-methylcyclohexyl)methanol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4α-Methylcyclohexane-1β-methanol

There total 17 articles about 4α-Methylcyclohexane-1β-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

trans-4-methylcyclohexanecarboxylic acid (934-67-8,4331-54-8,13064-83-0) → (trans-4-methylcyclohexyl)methanol (3937-49-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at -20 - -5 ℃; for 2.5h;

Reference yield: 91.0%

trans-4-methylcyclohexanecarbonyl chloride (55930-23-9) → (trans-4-methylcyclohexyl)methanol (3937-49-3)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

Reference yield: 88.0%

(4-methylcyclohex-3-en-1-yl)methanol (39155-38-9) → (trans-4-methylcyclohexyl)methanol (3937-49-3)

Guidance literature:

With hydrogen; [(bicyclo[2.2.1]hepta-2,5-diene)(1,4-bis(diphenylphosphino)butane)rhodium(I)] tetrafluoroborate; In dichloromethane; at 25 ℃; for 1h; under 33097.5 Torr;

DOI:10.1021/ja00325a030

upstream raw materials:

trans-4-methyl-1-(ethoxycarbonyl)cyclohexane

trans-4-methylcyclohexanecarboxylic acid

(4-methylcyclohex-3-en-1-yl)methanol

trans-4-methylcyclohexanecarbonyl chloride

Downstream raw materials:

trans-1-Chlormethyl-4-methyl-cyclohexan

trans-1-(bromomethyl)-4-methylcyclohexane

(trans-4-methyl-cyclohexyl)-acetic acid

trans-4-methylcyclohexylmethyl cyanide