Bis[4-fluorophenyl] sulfoxide

Base Information

• Chemical Name: Bis[4-fluorophenyl] sulfoxide
• CAS No.: 395-25-5
• Molecular Formula: C12H8F2OS
• Molecular Weight: 238.258
• Hs Code.: 2930909090
• Mol file: 395-25-5.mol

Synonyms:Benzene,1,1'-sulfinylbis[4-fluoro;di-(4-fluorophenyl)sulfoxide;bis(4-fluorophenyl)sulfoxide;di(p-fluorophenyl) sulphoxide;4,4'-difluorodiphenyl sulphoxide;bis(p-fluorophenyl)sulfoxide;

Chemical Property of Bis[4-fluorophenyl] sulfoxide

Chemical Property:

• Melting Point: 46.6-47.0℃ (hexane )
• PSA: 36.28000
• LogP: 3.99720

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Bis[4-fluorophenyl] sulfoxide

There total 8 articles about Bis[4-fluorophenyl] sulfoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

fluorobenzene (462-06-6) → bis(4-fluorophenyl)sulfoxide (395-25-5)

Guidance literature:

With thionyl chloride; In dichloromethane; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1080/10426500903496721

Reference yield: 86.0%

4,4'-difluorodiphenyl sulfide (404-38-6) → bis(4-fluorophenyl)sulfoxide (395-25-5)

Guidance literature:

With palladium; dihydrogen peroxide; In methanol; at 60 ℃; for 22h; chemoselective reaction; Green chemistry;

DOI:10.1039/c8ob03209b

Reference yield: 61.0%

thionyl chloride (7719-09-7) + fluorobenzene (462-06-6) → bis(4-fluorophenyl)sulfoxide (395-25-5)

Guidance literature:

With aluminum (III) chloride; silica gel;

DOI:10.1039/c3cc37795d

upstream raw materials:

fluorobenzene

α,α,α-trifluorotoluene

1,3,5-trimethyl-benzene

thionyl chloride

Downstream raw materials:

4,4'-difluorodiphenyl sulfide

bis(4-fluorophenyl)disulfide

MoO₂(2,6-bis(2,2-diphenyl-2-mercaptoethyl)pyridine^(2-))

MoO₂(2,6-bis(2,2'-diphenyl-2-thioethyl)pyridinate)

Refernces

• 1、 Li, Xing,Du, Jia,Zhang, Yongli,Chang, Honghong,Gao, Wenchao,Wei, Wenlong. "Synthesis and nano-Pd catalyzed chemoselective oxidation of symmetrical and unsymmetrical sulfides". . p. 3048 - 3055. Retrieved 2019/03/21.
• 2、 Baldassari, Lucas L.,Mantovani, Anderson C.,Senoner, Samuel,Maryasin, Boris,Maulide, Nuno,Lüdtke, Diogo S.. "Redox-Neutral Synthesis of Selenoesters by Oxyarylation of Selenoalkynes under Mild Conditions". supporting information. p. 5881 - 5885. Retrieved 2018/09/25.