1-Phenyl-4-(pyrrolidin-1-yl)-1,2,3,6-tetrahydro-1lambda~5~-phosphinin-1-one

Base Information

Chemical Name:1-Phenyl-4-(pyrrolidin-1-yl)-1,2,3,6-tetrahydro-1lambda~5~-phosphinin-1-one
CAS No.:39968-79-1
Molecular Formula:C15H20NOP
Molecular Weight:261.29900
Hs Code.:
DSSTox Substance ID:DTXSID20515707
Mol file:39968-79-1.mol

Synonyms:39968-79-1;DTXSID20515707;1-Phenyl-4-(pyrrolidin-1-yl)-1,2,3,6-tetrahydro-1lambda~5~-phosphinin-1-one

Suppliers and Price of 1-Phenyl-4-(pyrrolidin-1-yl)-1,2,3,6-tetrahydro-1lambda~5~-phosphinin-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Phenyl-4-(pyrrolidin-1-yl)-1,2,3,6-tetrahydro-1lambda~5~-phosphinin-1-one

Chemical Property:

PSA：30.12000
LogP:2.99630
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:261.128251259
Heavy Atom Count:18
Complexity:365

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN(C1)C2=CCP(=O)(CC2)C3=CC=CC=C3

Technology Process of 1-Phenyl-4-(pyrrolidin-1-yl)-1,2,3,6-tetrahydro-1lambda~5~-phosphinin-1-one

There total 2 articles about 1-Phenyl-4-(pyrrolidin-1-yl)-1,2,3,6-tetrahydro-1lambda~5~-phosphinin-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 123-75-1
pyrrolidine

: 38707-15-2
1-phenyl-4-phosphorinanone 1-oxide

: 39968-79-1
1,2,3,6-tetrahydro-1-phenyl-4-(1-pyrrolidinyl)phosphorin 1-oxide

Guidance literature:: With toluene-4-sulfonic acid; In chloroform; 1.) reflux, 3 h, 2.) 48 h, 0 deg C;

Reference yield:

: 23855-87-0
1-phenyl-4-phosphorinanone

: 39968-79-1
1,2,3,6-tetrahydro-1-phenyl-4-(1-pyrrolidinyl)phosphorin 1-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: 92.5 percent / 30 percent H₂O₂ / CHCl₃

2: 87 percent / p-toluenesulfonic acid / CHCl₃ / 1.) reflux, 3 h, 2.) 48 h, 0 deg C

With dihydrogen peroxide; toluene-4-sulfonic acid; In chloroform;