2,2,2-Trifluoro-n-[(1r)-1-phenylethyl]acetamide

Base Information

Chemical Name:2,2,2-Trifluoro-n-[(1r)-1-phenylethyl]acetamide
CAS No.:39995-50-1
Molecular Formula:C₁₀H₁₀F₃NO
Molecular Weight:217.191
Hs Code.:2924297099
DSSTox Substance ID:DTXSID40354670
Nikkaji Number:J52.460C
Wikidata:Q82132955
Mol file:39995-50-1.mol

Synonyms:39995-50-1;2,2,2-trifluoro-n-[(1r)-1-phenylethyl]acetamide;2,2,2-Trifluoro-N-[(R)-alpha-methylbenzyl]acetamide;(R)-2,2,2-Trifluoro-N-(1-phenylethyl)acetamide;(R)-1-Phenylethyltrifluoroacetamide;SCHEMBL22499610;DTXSID40354670;ZJFCMJDNHPXGBY-SSDOTTSWSA-N;CS-M0221;AKOS017382434;AS-68925;C12511;(2-ISOPROPYL-5-METHYL-PHENOXY)-ACETICACIDHYDRAZIDE;2,2,2-Trifluoro-N-[(R)-alpha-methylbenzyl]acetamide, 99%

Suppliers and Price of 2,2,2-Trifluoro-n-[(1r)-1-phenylethyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,2,2-Trifluoro-N-[(R)-α-methylbenzyl]acetamide
10mg
$ 45.00

Atlantic Research Chemicals
2,2,2-Trifluoro-N-[(1R)-1-phenylethyl]acetamide 95%
250mgs:
$ 91.90

American Custom Chemicals Corporation
2,2,2-TRIFLUORO-N-[(R)-ALPHA-METHYLBENZYL]ACETAMIDE 95.00%
5MG
$ 495.81

Total 4 raw suppliers

Chemical Property of 2,2,2-Trifluoro-n-[(1r)-1-phenylethyl]acetamide

Chemical Property:

Vapor Pressure:0.00434mmHg at 25°C
Melting Point:94-96oC(lit.)
Boiling Point:278.1oC at 760 mmHg
Flash Point:122oC
PSA：32.59000
Density:1.217g/cm3
LogP:3.26640
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:217.07144843
Heavy Atom Count:15
Complexity:221

Purity/Quality:

99%, ^*data from raw suppliers

2,2,2-Trifluoro-N-[(R)-α-methylbenzyl]acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=CC=C1)NC(=O)C(F)(F)F
Isomeric SMILES:C[C@H](C1=CC=CC=C1)NC(=O)C(F)(F)F

Technology Process of 2,2,2-Trifluoro-n-[(1r)-1-phenylethyl]acetamide

There total 15 articles about 2,2,2-Trifluoro-n-[(1r)-1-phenylethyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 3886-69-9
(R)-1-phenyl-ethyl-amine

: 183266-61-7
1-(trifluoroacetyl)benzotriazole

: 95-14-7,27556-51-0
1,2,3-Benzotriazole

: 2354-91-8,28332-81-2,39995-50-1,39995-51-2
N-<(R)-(+)-α-phenylethyl>-2,2,2-trifluoroacetamide

Guidance literature:: In tetrahydrofuran; for 4h; Ambient temperature;
DOI:10.1021/jo961537r

Reference yield: 100.0%

: 383-63-1
ethyl trifluoroacetate,

: 3886-69-9
(R)-1-phenyl-ethyl-amine

: 2354-91-8,28332-81-2,39995-50-1,39995-51-2
N-<(R)-(+)-α-phenylethyl>-2,2,2-trifluoroacetamide

Guidance literature:: With sodium hydride; In diethyl ether; at 0 - 20 ℃;
DOI:10.1002/1522-2675(20000906)83:9<2436::AID-HLCA2436>3.0.CO;2-N

Reference yield: 100.0%

: 62288-65-7
2,2,2-trifluoro-N-(1-phenylvinyl)acetamide

: 2354-91-8,28332-81-2,39995-50-1,39995-51-2
(S)-2,2,2-trifluoro-(α-methylbenzyl)acetamide

Guidance literature:: With Rh⁽¹⁺⁾*2CH₄O*C₄H₁₂B^(1-)*C₃₄H₄₀O₂P₂; hydrogen; In methanol; at 22 ℃; for 6h; under 750.075 Torr; enantioselective reaction; Inert atmosphere;
DOI:10.1002/adsc.201200780