p-Trifluoromethylbenzohydroxamic acid

Base Information

Chemical Name:p-Trifluoromethylbenzohydroxamic acid
CAS No.:40069-07-6
Molecular Formula:C8H6F3NO2
Molecular Weight:205.136
Hs Code.:
DSSTox Substance ID:DTXSID70343395
Nikkaji Number:J275.020A
Wikidata:Q82114684
ChEMBL ID:CHEMBL154630
Mol file:40069-07-6.mol

Synonyms:CHEMBL154630;p-trifluoromethylbenzohydroxamic acid;40069-07-6;N-Hydroxy-4-(trifluoromethyl)benzamide;IFLab1_005154;4-Trifluoromethylbenzohydroxamic acid;SCHEMBL14880225;DTXSID70343395;HMS1426K06;4-Trifluoromethylbenzohydroximic acid;BDBM50015176;N-Hydroxy-4-trifluoromethyl-benzamide;AKOS000181285;N-Hydroxy-4-(trifluoromethyl)benzamide #;4-(trifluoromethyl)benzenecarbohydroxamic acid;Z59181968

Suppliers and Price of p-Trifluoromethylbenzohydroxamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of p-Trifluoromethylbenzohydroxamic acid

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:205.03506292
Heavy Atom Count:14
Complexity:209

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)NO)C(F)(F)F

Technology Process of p-Trifluoromethylbenzohydroxamic acid

There total 6 articles about p-Trifluoromethylbenzohydroxamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 329-15-7
4-trifluoromethyl-phenyl acetyl chloride

: 40069-07-6
N-hydroxy-4-(trifluoromethyl)benzamide

Guidance literature:: With hydroxylamine hydrochloride; sodium carbonate; In diethyl ether; water; at 20 ℃; for 0.75h; Inert atmosphere;
DOI:10.1002/anie.202107148

Reference yield:

: 2967-66-0
methyl 4-(trifluoromethyl)benzoate

: 40069-07-6
N-hydroxy-4-(trifluoromethyl)benzamide

Guidance literature:: With hydroxylamine hydrochloride; potassium hydroxide; In methanol; at 20 ℃; for 12h; pH=10;
DOI:10.1002/ejoc.202001460

Reference yield:

: 455-24-3
4-trifluoromethylbenzoic acid

: 40069-07-6
N-hydroxy-4-(trifluoromethyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 0 - 20 °C

2: hydroxylamine hydrochloride; sodium hydroxide / tetrahydrofuran; water / 2 h / 20 °C

With oxalyl dichloride; hydroxylamine hydrochloride; N,N-dimethyl-formamide; sodium hydroxide; In tetrahydrofuran; dichloromethane; water;
DOI:10.1002/anie.201309198