3,5-Dimethoxystyrene

Base Information

• Chemical Name: 3,5-Dimethoxystyrene
• CAS No.: 40243-87-6
• Molecular Formula: C10H12O2
• Molecular Weight: 164.204
• DSSTox Substance ID: DTXSID70431125
• Nikkaji Number: J977.977I
• Mol file: 40243-87-6.mol

Synonyms:3,5-dimethoxystyrene;1-ethenyl-3,5-dimethoxybenzene;40243-87-6;Benzene, 1-ethenyl-3,5-dimethoxy-;SCHEMBL2017917;DTXSID70431125;YYDWZJCCIAMZIH-UHFFFAOYSA-N;AKOS013992395;CS-0239403;EN300-211983

Chemical Property of 3,5-Dimethoxystyrene

Chemical Property:

• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 164.083729621
• Heavy Atom Count: 12
• Complexity: 133

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1)C=C)OC

Technology Process of 3,5-Dimethoxystyrene

There total 33 articles about 3,5-Dimethoxystyrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3,5-dimethoxybenzaldehdye (7311-34-4) + methyl-triphenylphosphonium iodide (2065-66-9) → 3,5-dimethoxystyrene (40243-87-6)

Guidance literature:

methyl-triphenylphosphonium iodide; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 1h;

3,5-dimethoxybenzaldehdye; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 10h;

DOI:10.1016/j.ejmech.2017.06.006

Reference yield: 99.0%

3,5-dimethoxybenzaldehdye (7311-34-4) + Methyltriphenylphosphonium bromide (1779-49-3) → 3,5-dimethoxystyrene (40243-87-6)

Guidance literature:

Methyltriphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere;

3,5-dimethoxybenzaldehdye; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1039/c1cc13992d

Reference yield: 99.0%

3,5-dimethoxybenzaldehdye (7311-34-4) → 3,5-dimethoxystyrene (40243-87-6)

Guidance literature:

With Methyltriphenylphosphonium bromide; In tetrahydrofuran; for 2h; Reflux; Inert atmosphere;

upstream raw materials:

methanol

β-(3,5-Dimethoxyphenyl)ethanesulfonyl azide

ethene

3,5-dimethoxybenzoyl chloride

Downstream raw materials:

1-(3,5-dimethoxyphenyl)ethan-1-one

(E)-3,3'-dimethoxystilbene

(E)-3,3',5,5'-tetramethoxystilbene

1,2-bis(4-methoxyphenyl)ethene

Refernces

• 1、 Muniyasamy, Harikrishnan,Chinnadurai, Chithiraikumar,Nelson, Malini,Kubendran, Aravind Manikka,Sukumaran, Karthika,Balasubramaniem, Ashokkumar,Sepperumal, Murugesan,Ayyanar, Siva,Govindasamy, Mani,Ghfar, Ayman,Alsubaied, Fehaid Mohammed. "Highly selective flurogenic chemosensor for cyanide ion in aqueous medium and its applications of logic gate and Hela cells". . . Retrieved 2021.
• 2、 Zhang, Xu,Wang, Zhen-Yu,Wang, Xing,Xu, Hui,Dai, Hui-Xiong. "Functionalized styrene synthesis via palladium-catalyzed C[sbnd]C cleavage of aryl ketones". . . Retrieved 2022/03/31.