4-hydroxysphinganine (C17 base)

Base Information

• Chemical Name: 4-hydroxysphinganine (C17 base)
• CAS No.: 40289-37-0
• Molecular Formula: C17H37NO3
• Molecular Weight: 303.486
• Mol file: 40289-37-0.mol

Synonyms:(2S,3S,4R)-2-Amino-heptadecane-1,3,4-triol;

Chemical Property of 4-hydroxysphinganine (C17 base)

Chemical Property:

• PSA: 86.71000
• LogP: 3.42920

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-hydroxysphinganine (C17 base)

There total 2 articles about 4-hydroxysphinganine (C17 base) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

agelasphin-9a (148289-27-4) → methyl D-galactopyranoside (97-30-3,617-04-9,709-50-2,1824-94-8,2152-78-5,3149-68-6,3396-99-4,6819-48-3,18469-06-2,20550-04-3,22277-65-2,29411-57-2,35437-40-2,35437-43-5,36191-11-4,36191-12-5,39598-79-3,39598-80-6,39598-89-5,51023-63-3,51223-62-2,51224-38-5,51224-39-6,51224-40-9,51224-41-0,51819-81-9,51819-82-0,51819-83-1,56688-81-4,62279-53-2,64281-79-4,64281-80-7,64912-19-2,66101-73-3,78184-90-4,84368-39-8,84368-40-1,84368-41-2,92142-37-5,93302-26-2,103421-28-9,115794-08-6) + methyl (2R)-2-hydroxytetracosanoate (2433-95-6,54563-86-9,54563-85-8) + (2S,3S,4R)-2-amino-1,3,4-heptadecanetriol (40289-37-0)

Guidance literature:

With hydrogenchloride; In methanol; water; at 80 ℃; for 18h;

DOI:10.1016/S0040-4020(01)86991-X

Reference yield:

methanol (67-56-1) + agelasphin-9a (148289-27-4) → methyl D-galactopyranoside (97-30-3,617-04-9,709-50-2,1824-94-8,2152-78-5,3149-68-6,3396-99-4,6819-48-3,18469-06-2,20550-04-3,22277-65-2,29411-57-2,35437-40-2,35437-43-5,36191-11-4,36191-12-5,39598-79-3,39598-80-6,39598-89-5,51023-63-3,51223-62-2,51224-38-5,51224-39-6,51224-40-9,51224-41-0,51819-81-9,51819-82-0,51819-83-1,56688-81-4,62279-53-2,64281-79-4,64281-80-7,64912-19-2,66101-73-3,78184-90-4,84368-39-8,84368-40-1,84368-41-2,92142-37-5,93302-26-2,103421-28-9,115794-08-6) + methyl (2R)-2-hydroxytetracosanoate (2433-95-6,54563-86-9,54563-85-8) + (2S,3S,4R)-2-amino-1,3,4-heptadecanetriol (40289-37-0)

Guidance literature:

With hydrogenchloride; In water; at 80 ℃; for 18h;

DOI:10.1016/S0040-4020(01)86991-X

Reference yield: 61.0%

C30H50O4 (1282034-26-7) + (2S,3S,4R)-2-amino-1,3,4-heptadecanetriol (40289-37-0) → C47H85NO6 (1282034-41-6)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 5h; Inert atmosphere;

DOI:10.1002/anie.201006035

upstream raw materials:

methanol

agelasphin-9a

Downstream raw materials:

C₄₇H₈₅NO₆

C₈₀H₁₀₇NO₈

C₆₁H₉₃NO₈

Refernces