3'-O-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]thymidine

Base Information

Chemical Name:3'-O-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]thymidine
CAS No.:40615-37-0
Molecular Formula:C33H34N2O8
Molecular Weight:586.642
Hs Code.:
DSSTox Substance ID:DTXSID60559963
Nikkaji Number:J1.210.963F
Wikidata:Q82442872

Synonyms:40615-37-0;SCHEMBL5531135;DTXSID60559963;VINVRLVGJSZQQZ-FRXPANAUSA-N;3'-O-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]thymidine;5'-O-(4,4'-dimethoxytrityl)-3'-O-acetylthymidine

Suppliers and Price of 3'-O-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]thymidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of 3'-O-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]thymidine

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:11
Exact Mass:586.23151605
Heavy Atom Count:43
Complexity:986

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN(C(=O)NC1=O)C2CC(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OC(=O)C
Isomeric SMILES:CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OC(=O)C

Technology Process of 3'-O-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]thymidine

There total 5 articles about 3'-O-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]thymidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 108-24-7
acetic anhydride

: 40615-39-2
5'-O-(4-4'-dimethoxytrityl)thymidine

: 40615-37-0
3'-O-acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-3,4-dihydrothymidine

Guidance literature:: With pyridine; at 20 ℃; Inert atmosphere;
DOI:10.1002/chem.201700045

Reference yield:

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 40615-37-0
3'-O-acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-3,4-dihydrothymidine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 20 °C

2: pyridine / 20 °C

With pyridine;
DOI:10.1039/c0cc02028a

Reference yield:

: 50-89-5,28854-96-8,3545-96-8,50-88-4
thymidine

: 40615-37-0
3'-O-acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-3,4-dihydrothymidine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 20 °C

2: pyridine / 20 °C

With pyridine;
DOI:10.1039/c0cc02028a