[4-[1-(4-acetyloxyphenyl)-3-oxo-isobenzofuran-1-yl]phenyl] acetate

Base Information

• Chemical Name: [4-[1-(4-acetyloxyphenyl)-3-oxo-isobenzofuran-1-yl]phenyl] acetate
• CAS No.: 5449-84-3
• Molecular Formula: C24H18O6
• Molecular Weight: 402.403
• Mol file: 5449-84-3.mol

Synonyms:

Chemical Property of [4-[1-(4-acetyloxyphenyl)-3-oxo-isobenzofuran-1-yl]phenyl] acetate

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [4-[1-(4-acetyloxyphenyl)-3-oxo-isobenzofuran-1-yl]phenyl] acetate

There total 4 articles about [4-[1-(4-acetyloxyphenyl)-3-oxo-isobenzofuran-1-yl]phenyl] acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

phenolphthalein (77-09-8) + acetic anhydride (108-24-7) → phenolphthalein-4,4'-diyl diacetate (5449-84-3)

Guidance literature:

With Sulfate; titanium(IV) oxide; In dichloromethane; at 20 ℃; for 0.5h;

Reference yield: 95.0%

2-(4,4'-diacetoxy-benzhydryl)-benzoic acid (132794-10-6) → phenolphthalein-4,4'-diyl diacetate (5449-84-3)

Guidance literature:

With Iron(III) nitrate nonahydrate; sodium bromate; In acetonitrile; at 20 ℃; for 18h; Inert atmosphere; Irradiation; Sealed tube;

DOI:10.1021/acs.orglett.1c01984

Reference yield:

phthalic anhydride (85-44-9) → phenolphthalein-4,4'-diyl diacetate (5449-84-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / 115 - 120 °C / man kocht die erhaltene Schmelze mit Wasser aus und extrahiert mit verd. Natronlauge

With sulfuric acid;

upstream raw materials:

phenolphthalein

acetic anhydride

phthalic anhydride

phenol

Downstream raw materials:

phenolphthalin

acetic acid