3-(3-Bromopropyl)pyridine hydrobromide

Base Information

• Chemical Name: 3-(3-Bromopropyl)pyridine hydrobromide
• CAS No.: 41038-63-5
• Molecular Formula: BrH*C₈H₁₀BrN
• Molecular Weight: 280.99
• European Community (EC) Number: 837-831-0
• DSSTox Substance ID: DTXSID50507377
• Mol file: 41038-63-5.mol

Synonyms:3-(3-Bromopropyl)pyridine hydrobromide;41038-63-5;3-(3-Bromopropyl)pyridine Hydrobromide;3-(3-bromopropyl)pyridine;hydrobromide;3-(3-Pyridinyl)propyl Bromide Hydrobromide;SCHEMBL7412606;DTXSID50507377;KQVWDZPGKCWJOP-UHFFFAOYSA-N;3-(3-pyridyl)-1-bromopropane HBr;MFCD13186328;3-(3-Bromopropyl)pyridinehydrobromide;AKOS024397757;3-(3-pyridyl)propyl bromide hydrobromide;BS-37909;3-(3-pyridyl)-propyl bromide hydrobromide;FT-0663859;EN300-6735555;3-(3-Bromopropyl)pyridine--hydrogen bromide (1/1)

Chemical Property of 3-(3-Bromopropyl)pyridine hydrobromide

Chemical Property:

• PSA: 12.89000
• LogP: 3.36720
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 280.92378
• Heavy Atom Count: 11
• Complexity: 85.3

Purity/Quality:

98%Min ^*data from raw suppliers

3-(3-Bromopropyl)pyridineHydrobromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CN=C1)CCCBr.Br
• Uses: 3-(3-Bromopropyl)pyridine Hydrobromide is used for preparation of thiophene and pyrrole derivatives as platelet aggregation inhibitors.

Technology Process of 3-(3-Bromopropyl)pyridine hydrobromide

There total 3 articles about 3-(3-Bromopropyl)pyridine hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

3-(3-pyridyl)propan-1-ol (2859-67-8) → 3-(pyridin-3-yl)propyl bromide hydrobromide (41038-63-5)

Guidance literature:

With hydrogen bromide; for 5h; Heating;

Reference yield:

3-(3-Phenoxy-propyl)-pyridine → 3-(pyridin-3-yl)propyl bromide hydrobromide (41038-63-5)

Guidance literature:

With hydrogen bromide; Heating;

DOI:10.1021/jm00389a022

Reference yield:

3-Methylpyridine (108-99-6) → 3-(pyridin-3-yl)propyl bromide hydrobromide (41038-63-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Na, NH₃ (liq.) / 1.) -78 deg C, 1 h, 2.) RT, overnight

2: 48percent HBr / Heating

With ammonia; hydrogen bromide; sodium;

DOI:10.1021/jm00389a022

upstream raw materials:

3-(3-pyridyl)propan-1-ol

3-Methylpyridine

Downstream raw materials:

N-[3-(pyridin-3-yl)-propyl]-2,6-dimethylaniline

methyl 8-(p-chlorophenylsulfonamido)-4-[3-(pyridin-3-yl)propyl]-octanoate

CGS 22652

8-(4-Azido-benzenesulfonylamino)-4-(3-pyridin-3-yl-propyl)-octanoic acid methyl ester

Refernces

• 1、 -. "CERTAIN (ARYLSULFONAMIDO- AND IMIDAZOLYL-)-SUBSTITUTED CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND USE FOR SUPPRESSING THROMBOXANE ACTIVITY". . . Retrieved 2008/06/13.
• 2、 Made, A. W. van der,Nolte, R. J. M.,Drenth, W.. "On the mechanism of epoxidation of alkenes with hypochlorite, catalysed by manganese(III) tetraarylporphyrins". . p. 537 - 551. Retrieved 2007/10/02.