Ethyl [2-(cyclopent-1-en-1-yl)-6-methylphenyl]carbamate

Base Information

• Chemical Name: Ethyl [2-(cyclopent-1-en-1-yl)-6-methylphenyl]carbamate
• CAS No.: 410538-58-8
• Molecular Formula: C15H19NO2
• Molecular Weight: 245.321
• DSSTox Substance ID: DTXSID30573671
• Wikidata: Q82462465
• Mol file: 410538-58-8.mol

Synonyms:410538-58-8;DTXSID30573671;Ethyl [2-(cyclopent-1-en-1-yl)-6-methylphenyl]carbamate;6-(cyclopent-1-enyl)-N-ethoxycarbonyl-2-methylaniline

Chemical Property of Ethyl [2-(cyclopent-1-en-1-yl)-6-methylphenyl]carbamate

Chemical Property:

• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 245.141578849
• Heavy Atom Count: 18
• Complexity: 325

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)NC1=C(C=CC=C1C2=CCCC2)C

Technology Process of Ethyl [2-(cyclopent-1-en-1-yl)-6-methylphenyl]carbamate

There total 2 articles about Ethyl [2-(cyclopent-1-en-1-yl)-6-methylphenyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

6-(cyclopent-1-en-1-yl)-2-methyl-aniline (235779-09-6) + chloroformic acid ethyl ester (541-41-3) → ethyl N-[6-methyl-2-(cyclopent-1-enyl)phenyl]carbamate (410538-58-8)

Guidance literature:

With potassium carbonate; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1070/MC2001v011n05ABEH001489

Reference yield:

2-methyl-6-(cyclopent-2'-en-1'-yl)aniline (84487-47-8) → ethyl N-[6-methyl-2-(cyclopent-1-enyl)phenyl]carbamate (410538-58-8)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / 300 °C

2: K₂CO₃ / CH₂Cl₂ / 18 h / 20 °C

With potassium hydroxide; potassium carbonate; In dichloromethane;

DOI:10.1023/A:1015643505772

Reference yield: 65.0%

ethyl N-[6-methyl-2-(cyclopent-1-enyl)phenyl]carbamate (410538-58-8) → N-[6-(cyclopent-1-enyl)-2-methylphenyl]urea (474274-00-5)

Guidance literature:

With ammonia; In methanol; at 100 ℃; for 25h;

DOI:10.1023/A:1015020604764

upstream raw materials:

6-(cyclopent-1-en-1-yl)-2-methyl-aniline

chloroformic acid ethyl ester

2-methyl-6-(cyclopent-2'-en-1'-yl)aniline

Downstream raw materials:

N-[6-(cyclopent-1-enyl)-2-methylphenyl]urea