Ethyl 2-methyl-4-phenyl-1,3-thiazole-5-carboxylate

Base Information

Chemical Name:Ethyl 2-methyl-4-phenyl-1,3-thiazole-5-carboxylate
CAS No.:32043-95-1
Molecular Formula:C13H13 N O2 S
Molecular Weight:247.318
Hs Code.:2934100090
European Community (EC) Number:877-972-5
DSSTox Substance ID:DTXSID30427887
Nikkaji Number:J1.819.281K
Wikidata:Q82240621
ChEMBL ID:CHEMBL177177
Mol file:32043-95-1.mol

Synonyms:ethyl 2-methyl-4-phenyl-1,3-thiazole-5-carboxylate;32043-95-1;Ethyl 2-methyl-4-phenylthiazole-5-carboxylate;CHEMBL177177;SCHEMBL8823153;DTXSID30427887;MFCD07346320;AKOS016341454;MS-22325;BB 0238176;CS-0234749;FT-0716422;EN300-14684;J-018614;J-520769;2-Methyl-4-phenylthiazole-5-carboxylic acid ethyl ester;Z104442568;2-Methyl-4-phenyl-thiazole-5-carboxylic acid ethyl ester

Suppliers and Price of Ethyl 2-methyl-4-phenyl-1,3-thiazole-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl2-methyl-4-phenylthiazole-5-carboxylate 97%
5g
$ 564.00

American Custom Chemicals Corporation
ETHYL 2-METHYL-4-PHENYL-1,3-THIAZOLE-5-CARBOXYLATE 95.00%
5G
$ 1114.58

American Custom Chemicals Corporation
ETHYL 2-METHYL-4-PHENYL-1,3-THIAZOLE-5-CARBOXYLATE 95.00%
2.5G
$ 932.60

American Custom Chemicals Corporation
ETHYL 2-METHYL-4-PHENYL-1,3-THIAZOLE-5-CARBOXYLATE 95.00%
1G
$ 692.46

AK Scientific
Ethyl2-methyl-4-phenyl-1,3-thiazole-5-carboxylate
5g
$ 559.00

Total 5 raw suppliers

Chemical Property of Ethyl 2-methyl-4-phenyl-1,3-thiazole-5-carboxylate

Chemical Property:

Vapor Pressure:2.34E-06mmHg at 25°C
Melting Point:44 °C
Boiling Point:392.2°Cat760mmHg
PKA:1.00±0.10(Predicted)
Flash Point:191°C
PSA：67.43000
Density:1.188g/cm³
LogP:3.29520
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:247.06669983
Heavy Atom Count:17
Complexity:266

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl2-methyl-4-phenylthiazole-5-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(N=C(S1)C)C2=CC=CC=C2

Technology Process of Ethyl 2-methyl-4-phenyl-1,3-thiazole-5-carboxylate

There total 3 articles about Ethyl 2-methyl-4-phenyl-1,3-thiazole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 41381-97-9,146368-56-1
ethyl 2-chloro-3-oxo-3-phenylpropionate

: 62-55-5
thioacetamide

: 32043-95-1
2-methyl-4-phenyl-thiazole-5-carboxylic acid ethyl ester

Guidance literature:: With triethylamine;
DOI:10.1134/S1070427208030385

Reference yield:

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 62-55-5
thioacetamide

: 32043-95-1
2-methyl-4-phenyl-thiazole-5-carboxylic acid ethyl ester

Guidance literature:: ethyl 3-oxo-3-phenylpropionate; With hydroxy(phenyl)-λ³-iodanyl 2,4-dinitrobenzenesulfonate; In acetonitrile; at 120 ℃; for 0.00833333h;

thioacetamide; In acetonitrile; for 0.0166667h; Microwave irradiation;
DOI:10.1021/jm400840p

Reference yield:

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 32043-95-1
2-methyl-4-phenyl-thiazole-5-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuryl dichloride / tetrachloromethane / 1 h / 45 - 50 °C

2: ethanol / 6 h / 80 °C

With sulfuryl dichloride; In tetrachloromethane; ethanol;