Propane-1,3-di(sulfonyl chloride)

Base Information

• Chemical Name: Propane-1,3-di(sulfonyl chloride)
• CAS No.: 20686-91-3
• Molecular Formula: C3H6 Cl2 O4 S2
• Molecular Weight: 241.116
• Hs Code.: 2904909090
• Mol file: 20686-91-3.mol

Synonyms:1,3-Propanedisulfonylchloride (6CI,8CI); NSC 517262; Propane-1,3-disulfochloride

Chemical Property of Propane-1,3-di(sulfonyl chloride)

Chemical Property:

• Vapor Pressure: 0.000436mmHg at 25°C
• Boiling Point: 325.5°C at 760 mmHg
• Flash Point: 150.6°C
• PSA: 85.04000
• Density: 1.687g/cm³
• LogP: 2.67530

Purity/Quality:

99% ^*data from raw suppliers

Propane-1,3-disulfonyl dichloride 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Propane-1,3-di(sulfonyl chloride)

There total 13 articles about Propane-1,3-di(sulfonyl chloride) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1.3-propanedithiol (109-80-8) → 1,3-propanedisulfonyl dichloride (20686-91-3)

Guidance literature:

With dihydrogen peroxide; trichlorophosphate; In water; acetonitrile; at 25 ℃;

DOI:10.1016/j.tet.2012.04.040

Reference yield:

propane‐1,3‐diyl dicarbamimidothioate dihydrobromide (5442-32-0,64039-23-2) → 1,3-propanedisulfonyl dichloride (20686-91-3)

Guidance literature:

In diethyl ether; water; at 0 - 20 ℃; for 0.5h; Green chemistry;

DOI:10.1055/s-0033-1338567

Reference yield:

sodium α,ω-alkanedisulfonate (36589-58-9) → 1,3-propanedisulfonyl dichloride (20686-91-3)

Guidance literature:

With phosphorus pentachloride; at 20 - 110 ℃;

upstream raw materials:

propane

1,3-bis(thiocyanato)propane

2,6-dithia-heptanedioic acid diamide

1,3-bis-carbamimidoylmercapto-propane; diacetate

Downstream raw materials:

propane-1,3-disulfonic acid diphenyl ester

propane-1,3-disulfonic acid

Propandisulfonsaeure-(1,3)-dimethylester

3-phenoxysulfonyl-1-propanesulfonyl chloride

Refernces

• 1、 Sohrabnezhad, Samira,Bahrami, Kiumars,Hakimpoor, Farahman. "High yielding protocol for direct conversion of thiols to sulfonyl chlorides and sulfonamides". . p. 256 - 264. Retrieved 2019/02/06.
• 2、 Bahrami, Kiumars,Khodaei, Mohammad M.,Abbasi, Jamshid. "Synthesis of sulfonamides and sulfonic esters via reaction of amines and phenols with thiols using H2O2-POCl3 system". supporting information; experimental part. p. 5095 - 5101. Retrieved 2012/07/28.