6-Methyl-2-phenylquinoline-4-carbohydrazide

Base Information

Chemical Name:6-Methyl-2-phenylquinoline-4-carbohydrazide
CAS No.:41874-25-3
Molecular Formula:C17H15N3O
Molecular Weight:277.326
Hs Code.:
DSSTox Substance ID:DTXSID70534741
Wikidata:Q82408703
Mol file:41874-25-3.mol

Synonyms:6-methyl-2-phenylquinoline-4-carbohydrazide;DTXSID70534741

Suppliers and Price of 6-Methyl-2-phenylquinoline-4-carbohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 6-Methyl-2-phenylquinoline-4-carbohydrazide

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:277.121512110
Heavy Atom Count:21
Complexity:367

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)N=C(C=C2C(=O)NN)C3=CC=CC=C3

Technology Process of 6-Methyl-2-phenylquinoline-4-carbohydrazide

There total 9 articles about 6-Methyl-2-phenylquinoline-4-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 485-34-7
6-methyl-2-phenylquinoline-4-carboxylic acid ethyl ester

: 41874-25-3
6-methyl-2-phenylquinoline-4-carbohydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; at 100 ℃;
DOI:10.1021/acs.orglett.1c02267

Reference yield:

: 106-49-0,12221-03-3
p-toluidine

: 41874-25-3
6-methyl-2-phenylquinoline-4-carbohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1.1: iodine / dimethyl sulfoxide / 1 h / 100 °C / Sealed tube

1.2: 4 h / 100 °C / Sealed tube

2.1: hydrazine hydrate / ethanol / 100 °C

With iodine; hydrazine hydrate; In ethanol; dimethyl sulfoxide;
DOI:10.1021/acs.orglett.1c02267

Reference yield:

: 98-86-2
acetophenone

: 41874-25-3
6-methyl-2-phenylquinoline-4-carbohydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / water / Reflux

2: sulfuric acid / Reflux

3: hydrazine hydrate / 50 - 60 °C

With sulfuric acid; hydrazine hydrate; sodium hydroxide; In water;
DOI:10.1080/14756366.2016.1190714