1-Naphthalenecarboxaldehyde, 4-nitro-

Base Information

• Chemical Name: 1-Naphthalenecarboxaldehyde, 4-nitro-
• CAS No.: 42758-54-3
• Molecular Formula: C11H7NO3
• Molecular Weight: 201.17800
• Mol file: 42758-54-3.mol

Synonyms:4-Nitro-naphthalene-1-carbaldehyde;1-Naphthalenecarboxaldehyde,4-nitro;

Chemical Property of 1-Naphthalenecarboxaldehyde, 4-nitro-

Chemical Property:

• Melting Point: 106-107℃
• Boiling Point: 397.6±25.0 °C(Predicted)
• PSA: 62.89000
• Density: 1.368±0.06 g/cm3(Predicted)
• LogP: 3.08370

Purity/Quality:

98%Min ^*data from raw suppliers

4-Nitro-1-naphthaldehyde 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Naphthalenecarboxaldehyde, 4-nitro-

There total 7 articles about 1-Naphthalenecarboxaldehyde, 4-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

→ 4-nitro-1-naphthaldehyde (42758-54-3)

Guidance literature:

Reference yield:

para-[Bis(benzotriazol-1-yl)methyl]nitronapthalene (174708-77-1) → 4-nitro-1-naphthaldehyde (42758-54-3)

Guidance literature:

With hydrogenchloride; water; zinc dibromide; In 1,4-dioxane; for 4.5h; Yield given; Heating;

DOI:10.1016/0040-4039(95)02169-8

Reference yield:

1-Nitronaphthalene (86-57-7) → 4-nitro-1-naphthaldehyde (42758-54-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 50 percent / KOH / dimethylsulfoxide / 20 °C

2: 1.) ZnBr₂ 2.) HCl, water / dioxane / 4.5 h / Heating

With hydrogenchloride; potassium hydroxide; water; zinc dibromide; In 1,4-dioxane; dimethyl sulfoxide;

DOI:10.1016/0040-4039(95)02169-8

upstream raw materials:

4-Nitro-1-methoxymethyl-naphthalin

para-[Bis(benzotriazol-1-yl)methyl]nitronapthalene

acrylonitrile

3-methyl-2-(4-nitro-1-naphthyl)-2H-azirine

Downstream raw materials:

4-nitro-1-naphthoic acid

4-fluoro-1-naphthalenecarbaldehyde

Refernces

• 1、 -. "Oxazolone analogs as amyloid aggregation inhibitors and for the treatment of alzheimer's disease and disorders related to amyloidosis". . . Retrieved 2008/06/13.