1-Naphthalenecarboxylic acid, 4-nitro-

Base Information

• Chemical Name: 1-Naphthalenecarboxylic acid, 4-nitro-
• CAS No.: 1975-43-5
• Molecular Formula: C11H7NO4
• Molecular Weight: 217.181
• Mol file: 1975-43-5.mol

Synonyms:4-Nitro-naphthalene-1-carboxylic acid;4-nitro-[1]naphthoic acid;4-nitro-1-naphthalic acid;4-nitro-1-naphthalenecarboxylic acid;4-Nitro-1-naphthoic acid;4-nitronaphthalene-1-carboxylic acid;4-Nitro-[1]naphthoesaeure;

Chemical Property of 1-Naphthalenecarboxylic acid, 4-nitro-

Chemical Property:

• Melting Point: 218 - 219 °C
• Boiling Point: 448.8±28.0 °C(Predicted)
• PSA: 83.12000
• Density: 1.468±0.06 g/cm3(Predicted)
• LogP: 2.96940

Purity/Quality:

95% ^*data from raw suppliers

4-Nitro-1-naphthoicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Naphthalenecarboxylic acid, 4-nitro-

There total 18 articles about 1-Naphthalenecarboxylic acid, 4-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

carbon dioxide (124-38-9,18923-20-1) + 4-nitronaphthalen-1-yl pivalate (1533457-61-2) → 4-nitro-1-naphthoic acid (1975-43-5)

Guidance literature:

With 1,1'-bis-(diphenylphosphino)ferrocene; manganese; [1,1'-bis(diphenylphosphino)ferrocene]nickel(II) chloride; In N,N-dimethyl acetamide; at 80 ℃; for 48h; under 760.051 Torr; Schlenk technique;

DOI:10.1021/ja410883p

Reference yield: 66.0%

4-nitronaphthalic-1,8-anhydride (6642-29-1) → 4-nitro-1-naphthoic acid (1975-43-5)

Guidance literature:

4-nitronaphthalic-1,8-anhydride; With sodium hydroxide; mercury(II) oxide; In water; acetic acid; for 50h; Heating;

With hydrogenchloride; for 3h; Further stages.; Heating;

DOI:10.1021/jm990630f

Reference yield: 37.0%

4-Nitronaphthalene-1-carbonitrile (23245-63-8) → 4-nitro-1-naphthoic acid (1975-43-5)

Guidance literature:

With sulfuric acid; acetic acid; at 120 ℃; for 4h;

DOI:10.1135/cccc20000385

upstream raw materials:

4-nitro-1-methylnaphthalene

4-Nitronaphthalene-1-carbonitrile

4-nitro-[1]naphthoic acid amide

4-nitro-1-naphthaldehyde

Downstream raw materials:

4-Amino-1-naphthoic acid

1-amino-naphthalene

N-[[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]-1-naphthalenyl]carbonyl]L-glutamic acid

C₆₆H₆₁N₇O₅P₂

Refernces

• 1、 Markees,D.G.. "-". . p. 1382 - 1384. Retrieved 1973.
• 2、 Moseley, Jonathan D.,Gilday, John P.. "The mercury-mediated decarboxylation (Pesci reaction) of naphthoic anhydrides investigated by microwave synthesis". . p. 4690 - 4697. Retrieved 2007/10/03.