2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-4a,5-dimethyl-, cis-

Base Information

• Chemical Name: 2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-4a,5-dimethyl-, cis-
• CAS No.: 43209-93-4
• Molecular Formula: C₁₂H₁₈O
• Molecular Weight: 178.274
• Mol file: 43209-93-4.mol

Synonyms:

Chemical Property of 2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-4a,5-dimethyl-, cis-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-4a,5-dimethyl-, cis-

There total 1 articles about 2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-4a,5-dimethyl-, cis- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ trans-5,10-Dimethyl-Δ1(9)-oktalon-(2) (20536-77-0,20536-80-5,43209-93-4,43209-94-5,93777-43-6,105088-15-1,121843-02-5)

Guidance literature:

2,3-Dimethyl-cyclohexanon u. Methyl-vinylketon (NaOCH3, -10grad) ( im Gemisch mit d. cis-Form);

DOI:10.1016/S0040-4039(00)89516-7

Reference yield:

(rel-4aS,5R)-4a,5-dimethyl-4,4a5,6,7,8-hexahydronaphthalen-2(3H)-one (43209-93-4) → 4,4a,5,6,7,8-hexahydro-4a,5-dimethyl-1-phenylthionaphthalen-2(3H)-one (76015-85-5)

Guidance literature:

Multi-step reaction with 4 steps

1: lithium aluminium hydride / diethyl ether

2: 2.74 g / m-chloroperbenzoic acid / CH₂Cl₂ / 0.67 h / Ambient temperature

3: 68 percent / Jones reagent / acetone

4: 94 percent / aq. sodium hydroxide / ethanol / Ambient temperature

With sodium hydroxide; lithium aluminium tetrahydride; jones reagent; 3-chloro-benzenecarboperoxoic acid; In diethyl ether; ethanol; dichloromethane; acetone;

Reference yield:

(rel-4aS,5R)-4a,5-dimethyl-4,4a5,6,7,8-hexahydronaphthalen-2(3H)-one (43209-93-4) → (4aR,5S)-1-Benzenesulfinyl-4a,5-dimethyl-4,4a,5,6,7,8-hexahydro-3H-naphthalen-2-one (76015-86-6)

Guidance literature:

Multi-step reaction with 5 steps

1: lithium aluminium hydride / diethyl ether

2: 2.74 g / m-chloroperbenzoic acid / CH₂Cl₂ / 0.67 h / Ambient temperature

3: 68 percent / Jones reagent / acetone

4: 94 percent / aq. sodium hydroxide / ethanol / Ambient temperature

5: 74 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 0.33 h / Ambient temperature

With sodium hydroxide; lithium aluminium tetrahydride; jones reagent; 3-chloro-benzenecarboperoxoic acid; In diethyl ether; ethanol; dichloromethane; acetone;

Downstream raw materials:

racemic shwarane

2-((2S,4aS,8R,8aS)-8,8a-Dimethyl-4-oxo-decahydro-naphthalen-2-yl)-acrylic acid

(3R,4aS,5R)-3-Isopropenyl-4a,5-dimethyl-4,4a,5,6,7,8-hexahydro-3H-naphthalen-2-one

4,4a,5,6,7,8-hexahydro-4a,5-dimethyl-1-phenylthionaphthalen-2(3H)-one