Benzenemethanol, 2-hydroxy-3-(1-methylethyl)-

Base Information

Chemical Name:Benzenemethanol, 2-hydroxy-3-(1-methylethyl)-
CAS No.:4397-16-4
Molecular Formula:C10H14O2
Molecular Weight:166.22
Hs Code.:
DSSTox Substance ID:DTXSID901267680

Synonyms:4397-16-4;Benzenemethanol, 2-hydroxy-3-(1-methylethyl)-;SCHEMBL2927393;DTXSID901267680;2-Hydroxy-3-(1-methylethyl)benzenemethanol;benzenemethanol,2-hydroxy-3-(1-methylethyl)-

Suppliers and Price of Benzenemethanol, 2-hydroxy-3-(1-methylethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Benzenemethanol, 2-hydroxy-3-(1-methylethyl)-

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:166.099379685
Heavy Atom Count:12
Complexity:134

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=CC=CC(=C1O)CO

Technology Process of Benzenemethanol, 2-hydroxy-3-(1-methylethyl)-

There total 4 articles about Benzenemethanol, 2-hydroxy-3-(1-methylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 67372-96-7
3-isopropylsalicylaldehyde

: 4397-16-4
2-hydroxymethyl-6-isopropylphenol

Guidance literature:: With methanol; sodium tetrahydroborate;
DOI:10.1021/ja993598n

Reference yield: 90.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 88-69-7
2-(1-methylethyl)phenol

: 4397-16-4
2-hydroxymethyl-6-isopropylphenol

Guidance literature:: With diethylaluminium chloride; In dichloromethane; toluene; at -30 - 20 ℃; for 3h; Inert atmosphere;
DOI:10.1021/acs.joc.1c00560

Reference yield:

: 88-69-7
2-(1-methylethyl)phenol

: 4397-16-4
2-hydroxymethyl-6-isopropylphenol

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / 2,6-lutidine; PhMe; SnCl₄

2: 96 percent / NaBH₄; MeOH

With 2,6-dimethylpyridine; methanol; sodium tetrahydroborate; tin(IV) chloride; toluene; 1: Carboxylation / 2: Hydrogenation;
DOI:10.1021/ja993598n