67372-96-7Relevant articles and documents
New water soluble bis-imidazolium salts with a saldach scaffold: Synthesis, characterization and in vitro cytotoxicity/bactericidal studies
Elshaarawy, Reda F.M.,Kheiralla, Zeinab H.,Rushdy, Abeer A.,Janiak, Christoph
, p. 110 - 122 (2014)
A series of water-soluble bis-imidazolium salts of the type H 2(iPr)2saldach(1,2-Me2Im +-X-)2 (4) and their mononuclear complexes [M(III)Cl{(iPr)2saldach(1,2-Me2Im +-X-)2}] (M = Mn, 5; Fe, 6), (X = Cl, a; PF6, b; BF4, c), where saldach = N,N′- bis(salicylidene)-(±)-trans-1,2-diaminocyclohexane, have been synthesized and characterized using elemental analysis, electronic, spectral, magnetic as well as conductometric methods and MALDI-TOF-, ESI-MS. All complexes possess a distorted square pyramidal coordination geometry with MN2O 2Cl chromophore, as revealed by the elemental, spectral and literature data. These salts have been evaluated for in vitro cytotoxicity against HepG-2 and MCF-7 cell lines. Among them, 4c (IC50 = 22.17 μM) exhibited potency against MCF-7. The bactericidal efficacy of 4a-c was screened against a panel of common pathogenic bacteria. Compound 4a was found to be the most potent antibacterial agent and could inhibit all the bacterial strains more effectively than standard antibiotics.
UHMWPE with short-chain branches synthesized by alkenyl substituted phenoxy–imine catalysts in ethylene polymerization
Wang, Yi,Fan, Hong,Li, Bo-Geng
, p. 3808 - 3818 (2016)
The alkenyl substituted phenoxy–imine complexes [2-C3H5-6-(2, 3, 5, 6-C6F4H-N?CH)C6H3O]2TiCl2 (C3H5=?CH2? CH?CH2 or ?CH?CH?
Ionic Sal-SG Schiff bases as new synergetic chemotherapeutic candidates: Synthesis, metalation with Pd(ii) and in vitro pharmacological evaluation
Elshaarawy, Reda F. M.,Mostafa, Tahia B.,Refaee, Ayaat A.,El-Sawi, Emtithal A.
, p. 68260 - 68269 (2015/09/01)
A series of novel N-(salicylidene)-sulfaguanidines (Sal-SG) bearing ionic liquid (IL) terminals (ILSSGH, 4a-f) have been synthesized by Schiff base condensation of IL-functionalized salicylaldehydes (ILSal, 3a-g) and sulfaguanidine (SG). Metalation trials of these ionic Schiff bases with palladium(ii) chloride affords the corresponding Pd(ii) complexes, [Pd(ii)(ILSSG)Cl(H2O)] (5a-g). Further, the antimicrobial profiles of the new compounds against a set of common pathogens have been described. Zone of inhibition (ZOI) and minimal inhibitory concentration (MIC) values revealed that most of the new compounds exhibited significant antibacterial and potential inhibitory activity against Staphylococcus aureus (S. aureus), and this activity is modulated by substituents attached to the ionic liquid core as well as the counter-ion.
