67372-96-7

Upstream product

• 88-69-7 2-(1-methylethyl)phenol 
• 100-97-0 hexamethylenetetramine 
• 50-00-0 formaldehyd 
• 122-51-0 orthoformic acid triethyl ester 
• 74927-05-2 3-isopropyl-2-(methoxymethoxy)benzaldehyde 
• 74-96-4 ethyl bromide 
• 500362-00-5 C₁₂H₁₆O₂ 
• 67-66-3 chloroform 
• 89-83-8 thymol 
• 74931-59-2 1-isopropyl-2-methoxymethyloxybenzene 
• 108-24-7 acetic anhydride 
• 1666-00-8 2-hydroxyl-3-isopropyl-6-methylbenzaldehyde 

Downstream Products

• 75073-41-5 N-(2-hydroxy-3-isopropylthiobenzoyl)piperidine 
• 215033-68-4 N-(3-isopropylsalicylidene)aniline 
• 91969-75-4 3-isopropyl-2-methoxybenzaldehyde 
• 178547-21-2 2-(benzyloxy)-3-isopropylbenzaldehyde 
• 1233691-16-1 2-((2S,4S,5R)-3,4-dimethyl-5-phenyl-oxazolidyn-2-yl)-6-isopropylphenol 
• 165620-75-7 2-iPr-6-(CH=NiPr)C₆H₃OH 
• 1428321-11-2 C₂₆H₂₈N₂O₂ 
• 1428321-12-3 C₃₀H₃₀N₂O₂ 
• 1608109-07-4 (1R,2S,3R,4S)-3-((E)-(2-hydroxy-3-isopropylbenzylidene)amino)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol 

Relevant academic research and scientific papers

New water soluble bis-imidazolium salts with a saldach scaffold: Synthesis, characterization and in vitro cytotoxicity/bactericidal studies

A series of water-soluble bis-imidazolium salts of the type H 2(iPr)2saldach(1,2-Me2Im +-X-)2 (4) and their mononuclear complexes [M(III)Cl{(iPr)2saldach(1,2-Me2Im +-X-)2}] (M = Mn, 5; Fe, 6), (X = Cl, a; PF6, b; BF4, c), where saldach = N,N′- bis(salicylidene)-(±)-trans-1,2-diaminocyclohexane, have been synthesized and characterized using elemental analysis, electronic, spectral, magnetic as well as conductometric methods and MALDI-TOF-, ESI-MS. All complexes possess a distorted square pyramidal coordination geometry with MN2O 2Cl chromophore, as revealed by the elemental, spectral and literature data. These salts have been evaluated for in vitro cytotoxicity against HepG-2 and MCF-7 cell lines. Among them, 4c (IC50 = 22.17 μM) exhibited potency against MCF-7. The bactericidal efficacy of 4a-c was screened against a panel of common pathogenic bacteria. Compound 4a was found to be the most potent antibacterial agent and could inhibit all the bacterial strains more effectively than standard antibiotics.

Co-delivery of imidazolium Zn(II)salen and Origanum Syriacum essential oil by shrimp chitosan nanoparticles for antimicrobial applications

This study reports preparation and physicochemical characterization of natural antimicrobials (Origanum Syriacum essential oil (OSEO), shrimp chitosan nanoparticles (CSNPs)) and new imidazolium ionic liquid-supported Zn(II)Salen. These antimicrobials were

UHMWPE with short-chain branches synthesized by alkenyl substituted phenoxy–imine catalysts in ethylene polymerization

The alkenyl substituted phenoxy–imine complexes [2-C3H5-6-(2, 3, 5, 6-C6F4H-N?CH)C6H3O]2TiCl2 (C3H5=?CH2? CH?CH2 or ?CH?CH?

67Ga-metalloprobes: monitoring the impact of geometrical isomers on accumulation profiles in rat cardiomyoblasts and human breast carcinoma cells

Geometrically similar monocationic gallium(iii) complexes and their radiolabeled SPECT counterparts were obtained from Schiff base precursor ligands using ligand exchange reactions to evaluate the impact of cis and trans-isomers on their cellular accumula

Ionic Sal-SG Schiff bases as new synergetic chemotherapeutic candidates: Synthesis, metalation with Pd(ii) and in vitro pharmacological evaluation

A series of novel N-(salicylidene)-sulfaguanidines (Sal-SG) bearing ionic liquid (IL) terminals (ILSSGH, 4a-f) have been synthesized by Schiff base condensation of IL-functionalized salicylaldehydes (ILSal, 3a-g) and sulfaguanidine (SG). Metalation trials of these ionic Schiff bases with palladium(ii) chloride affords the corresponding Pd(ii) complexes, [Pd(ii)(ILSSG)Cl(H2O)] (5a-g). Further, the antimicrobial profiles of the new compounds against a set of common pathogens have been described. Zone of inhibition (ZOI) and minimal inhibitory concentration (MIC) values revealed that most of the new compounds exhibited significant antibacterial and potential inhibitory activity against Staphylococcus aureus (S. aureus), and this activity is modulated by substituents attached to the ionic liquid core as well as the counter-ion.

Iron(iii)-salan complexes catalysed highly enantioselective fluorination and hydroxylation of β-keto esters and N-Boc oxindoles

Chiral iron(iii)-salan complexes catalysed highly enantioselective α-fluorination and α-hydroxylation of β-keto esters and N-Boc oxindoles to give the corresponding products in high yields and good-to-excellent ee values under mild reaction conditions. This journal is the Partner Organisations 2014.

Asymmetric induction via short-lived chiral enolates with a chiral C-O axis

A novel method has been developed for the asymmetric cyclization of alkyl aryl ethers. The reactions were assumed to proceed via short-lived chiral enolate intermediates with a chiral C-O axis to give cyclic ethers with tetrasubstituted carbon in up to 99% ee. The half-life of racemization of the chiral enolate intermediate was roughly estimated to be ～1 s at -78 C.

Enantioselective intramolecular formal [2 + 4] annulation of acrylates and α,β-unsaturated imines catalyzed by amino acid derived phosphines

The first chiral phosphine-catalyzed activation of acrylates for intramolecular formal [2 + 4] reactions with unsaturated imines is described. The catalytic reactions afford N-heterocycles with exceptionally high diastereo- and enantioselectivities. The [2 + 4] products are amenable for further transformations to useful molecules such as chiral piperidines and multicyclic structures.

Large ultra-high molecular weight polyethylene spherical particles produced by AlR3 activated half-sandwich chromium(iii) catalysts

A series of half-sandwich pentamethylcyclopentadienyl chromium(iii) complexes bearing a salicylaldiminato ligand, Cp*[2-R1-4-R 2-6-(CHNR3)C6H2O]CrCl [R1 = iPr (1, 4), tBu (2, 3, 5), Ad (6); R2 = H (1, 2, 3), tBu (4, 5, 6); R3 = iPr (1, 2, 5, 6), tBu (3, 4)], were synthesized. All complexes were characterized by elemental analyses and the structures of complexes 1-4 and 6 were determined by X-ray diffraction analysis. These complexes adopt a pseudo-octahedral coordination environment with a three-legged piano stool geometry. Upon activation with a small amount of AlR3, complexes 1-6 all catalyze the polymerization of ethylene in a quasi living fashion with good to high catalytic activity under mild conditions and produce ultra-high molecular weight polyethylene as spherical particles with a diameter of 1-6 mm. The catalytic activity of these complexes and the molecular weight of the produced polyethylene can be tuned in a broad range by changing the R1, R 2, and R3 groups as well as the AlR3 cocatalyst. It was found that complex 6 with R1 = Ad, R2 = tBu, and R3 = iPr shows the highest catalytic activity and produces polyethylene with the highest molecular weight. The Royal Society of Chemistry 2011.

Expeditious synthesis of benzopyrans via lewis acid-catalyzed C-H functionalization: Remarkable enhancement of reactivity by an ortho substituent

An expeditious construction of a benzopyran skeleton via Lewis acid-catalyzed C-H functionalization was achieved. In this process, a [1,5] hydride shift and 6-endo cyclization successively occurred to give benzopyrans. The presence of substituents ortho to the alkoxy group significantly enhanced the reactivity, affording the desired compounds in excellent chemical yields with short reaction times.