Bis(benzothiazole-2-yl) ketone

Base Information

• Chemical Name: Bis(benzothiazole-2-yl) ketone
• CAS No.: 4464-60-2
• Molecular Formula: C15H8N2OS2
• Molecular Weight: 296.36700
• Hs Code.: 2934200090
• Mol file: 4464-60-2.mol

Synonyms:bis(1,3-benzothiazol-2-yl)methanone;

Chemical Property of Bis(benzothiazole-2-yl) ketone

Chemical Property:

• PSA: 99.33000
• LogP: 4.13700
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

Bis(benzo[d]thiazol-2-yl)methanone 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Bis(benzothiazole-2-yl) ketone

There total 8 articles about Bis(benzothiazole-2-yl) ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

di(1-methylbenzimidazol-2-yl)methane (1945-78-4) → bis(1,3-benzothiazol-2-yl)methanone (4464-60-2)

Guidance literature:

With air; triethylamine; In dimethyl sulfoxide; for 12h; Ambient temperature;

Reference yield: 74.0%

2-(trimethylsilyl)benzothiazole (32137-73-8) + phosgene (75-44-5) → bis(1,3-benzothiazol-2-yl)methanone (4464-60-2)

Guidance literature:

In dichloromethane; at 0 ℃; for 15h;

Reference yield: 43.0%

→ bis(1,3-benzothiazol-2-yl)methanone (4464-60-2)

Guidance literature:

With n-butyllithium; In toluene; at 20 ℃; for 2h; Cooling with acetone-dry ice;

With oxygen; In toluene;

upstream raw materials:

1,3-Benzothiazole

oxalyl dichloride

2-(trimethylsilyl)benzothiazole

phosgene

Downstream raw materials:

2,2'-[(2-methylphenoxy)methylene]bis(1,3-benzothiazole)

bis(1,3-benzothiazol-2-yl)(2-methylphenyl)methanol

ethyl 3-[bis(1,3-benzothiazol-2-yl)methoxy]benzoate

ethyl 3-[bis(1,3-benzothiazol-2-yl)(hydroxy)methyl]benzoate

Refernces

• 1、 -. "Multinucleated late transient metal olefin polymerization catalyst". Paragraph 0389; 0390; 0391; 0392. . Retrieved 2016/10/08.
• 2、 Nagasaki, Izuru,Suzuki, Yumiko,Iwamoto, Ken-Ichi,Higashino, Takeo,Miyashita, Akira. "Synthesis of heteroarenecarbonitriles by electrophilic cyanation; Reaction of metalated heteroarenes with p-toluenesulfonyl cyanide". . p. 443 - 450. Retrieved 2007/10/03.