2,5-DIACETOXYHEXANE

Base Information

• Chemical Name: 2,5-DIACETOXYHEXANE
• CAS No.: 10299-35-1
• Molecular Formula: C10H18 O4
• Molecular Weight: 202.24752
• Hs Code.: 2915390090
• Mol file: 10299-35-1.mol

Synonyms:2,5-Hexanediol,diacetate (6CI,7CI,8CI,9CI); 2,5-Diacetoxyhexane; NSC 78970

Chemical Property of 2,5-DIACETOXYHEXANE

Chemical Property:

• Vapor Pressure: 0.0182mmHg at 25°C
• Refractive Index: 1.4210-1.4250
• Boiling Point: 253.5°Cat760mmHg
• Flash Point: 115.7°C
• PSA: 52.60000
• Density: 1.004g/cm³
• LogP: 1.66980

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,5-Diacetoxyhexane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,5-DIACETOXYHEXANE

There total 10 articles about 2,5-DIACETOXYHEXANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

hexane-2,5-diol (2935-44-6) + acetic anhydride (108-24-7) → 2,5-Diacetoxy-hexan (10299-35-1)

Guidance literature:

With copper(II) bis(trifluoromethanesulfonate); In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/S0040-4020(01)01229-7

Reference yield: 91.0%

2,5-dimethyltetrahydrofuran (1003-38-9) + acetic anhydride (108-24-7) → 2,5-Diacetoxy-hexan (10299-35-1)

Guidance literature:

With aminosulfonic acid; In acetic acid; at 60 ℃; for 4h;

DOI:10.1016/j.tetlet.2004.07.024

Reference yield: 85.0%

hexane-2,5-diol (2935-44-6) + ethyl acetate (141-78-6) → 2,5-Diacetoxy-hexan (10299-35-1)

Guidance literature:

With aluminum oxide; monoaluminum phosphate; at 77 ℃;

upstream raw materials:

hexane-2,5-diol

2,5-diiodo-hexane

silver(I) acetate

3-hexyn-2,5-diol

Refernces

• 1、 Wang, Bo,Gu, Yanlong,Gong, Weizhong,Kang, Yuru,Yang, Liming,Suo, Jishuan. "Sulfamic acid as a cost-effective catalyst instead of metal-containing acids for acetolysis of cyclic ethers". . p. 6599 - 6602. Retrieved 2004.
• 2、 León, Félix,Francos, Javier,López-Serrano, Joaquín,García-Garrido, Sergio E.,Cadierno, Victorio,Pizzano, Antonio. "Double asymmetric hydrogenation of conjugated dienes: a self-breeding chirality route for C2 symmetric 1,4-diols". supporting information. p. 786 - 789. Retrieved 2019/01/21.