4-bromo-1-methyl-1H-pyrazole-5-carbaldehyde

Base Information

Chemical Name:4-bromo-1-methyl-1H-pyrazole-5-carbaldehyde
CAS No.:473528-88-0
Molecular Formula:C5H5BrN2O
Molecular Weight:189.011
Hs Code.:2933199090
European Community (EC) Number:817-042-8
DSSTox Substance ID:DTXSID50383279
Wikidata:Q82174950
Mol file:473528-88-0.mol

Synonyms:4-bromo-1-methyl-1H-pyrazole-5-carbaldehyde;473528-88-0;4-bromo-2-methylpyrazole-3-carbaldehyde;4-Bromo-1-methylpyrazole-5-carbaldehyde;1H-Pyrazole-5-carboxaldehyde, 4-bromo-1-methyl-;MFCD03074341;4-Bromo-2-methyl-2H-pyrazole-3-carbaldehyde;4-bromo-1-methyl-1h-pyrazole-5-carboxaldehyde;SCHEMBL568791;DTXSID50383279;GXAHYXQWHWDEDY-UHFFFAOYSA-N;AMY32901;BBL038343;STK301772;AKOS000308236;AS-8345;BP-10305;SY025533;4-bromo-1-methylpyrazole-5-carboxaldehyde;2-(4-CHLOROPHENYL)ETHYLISOTHIOCYANATE;CS-0045018;FT-0617711;EN300-92355;4-bromo-2-methyl-2 h-pyrazole-3-carbaldehyde;J-514562;J-514564;Z275128484;4-Bromo-1-methyl-1H-pyrazole-3-carbaldehyde

Suppliers and Price of 4-bromo-1-methyl-1H-pyrazole-5-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Bromo-1-methylpyrazole-5-carbaldehyde
250mg
$ 60.00

SynQuest Laboratories
4-Bromo-1-methyl-1H-pyrazole-5-carboxaldehyde
1 g
$ 138.00

Matrix Scientific
4-Bromo-1-methyl-1H-pyrazole-5-carbaldehyde 97%
1g
$ 341.00

Frontier Specialty Chemicals
4-Bromo-1-methyl-1H-pyrazole-5-carboxaldehyde 95%
1g
$ 45.00

Frontier Specialty Chemicals
4-Bromo-1-methyl-1H-pyrazole-5-carboxaldehyde 95%
5g
$ 150.00

Crysdot
4-Bromo-1-methyl-1H-pyrazole-5-carbaldehyde 97%
10g
$ 456.00

CHESS?
AD018795:4-Bromo-2-methyl-2H-pyrazole-3-carbaldehyde 95
1 g
$ 540.00

Chemenu
4-bromo-1-methyl-1H-pyrazole-5-carbaldehyde 95+%
5g
$ 284.00

Chemenu
4-bromo-1-methyl-1H-pyrazole-5-carbaldehyde 95+%
10g
$ 565.00

Chemenu
4-bromo-1-methyl-1H-pyrazole-5-carbaldehyde 95+%
1g
$ 96.00

Total 22 raw suppliers

Chemical Property of 4-bromo-1-methyl-1H-pyrazole-5-carbaldehyde

Chemical Property:

Melting Point:102-103°C
Boiling Point:275.2 °C at 760 mmHg
PKA:-1.48±0.10(Predicted)
Flash Point:120.2 °C
PSA：34.89000
Density:1.73 g/cm³
LogP:0.99510
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Sensitive.:Air Sensitive
XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:187.95853
Heavy Atom Count:9
Complexity:120

Purity/Quality:

99%, ^*data from raw suppliers

4-Bromo-1-methylpyrazole-5-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.;
Hazard Codes: Xi:Irritant;
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=C(C=N1)Br)C=O

Technology Process of 4-bromo-1-methyl-1H-pyrazole-5-carbaldehyde

There total 2 articles about 4-bromo-1-methyl-1H-pyrazole-5-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 27258-33-9
1-methyl-1H-pyrazole-5-carbaldehyde

: 473528-88-0
4-bromo-1-methyl-1H-pyrazole-5-carboxaldehyde

Guidance literature:: With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 1269291-90-8
5-(dimethoxymethyl)-1-methyl-1H-pyrazole

: 473528-88-0
4-bromo-1-methyl-1H-pyrazole-5-carboxaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / tetrahydrofuran; water / 48 h / 0 - 20 °C

2: N-Bromosuccinimide / N,N-dimethyl-formamide / 20 °C

With hydrogenchloride; N-Bromosuccinimide; In tetrahydrofuran; water; N,N-dimethyl-formamide;

Reference yield: 99.0%

: 473528-88-0
4-bromo-1-methyl-1H-pyrazole-5-carboxaldehyde

: 637-89-8
4-sulfanylphenol

: C₁₁H₁₀N₂O₂S

Guidance literature:: With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-ethyl-N,N-diisopropylamine; In toluene; at 110 ℃; for 16h; Inert atmosphere;