2-Ethyl-1,3-benzoxazol-4-amine

Base Information

Chemical Name:2-Ethyl-1,3-benzoxazol-4-amine
CAS No.:477603-35-3
Molecular Formula:C₉H₁₀N₂O
Molecular Weight:162.191
Hs Code.:2934999090
ChEMBL ID:CHEMBL567844
DSSTox Substance ID:DTXSID10476979
Wikidata:Q82308980
Mol file:477603-35-3.mol

Synonyms:2-Ethyl-1,3-benzoxazol-4-amine;477603-35-3;2-ethylbenzo[d]oxazol-4-amine;4-Amino-2-ethyl-1,3-benzoxazole;CHEMBL567844;SCHEMBL1917749;DTXSID10476979;ASWXQMIZDXNTKA-UHFFFAOYSA-N;CUA60335;2-ETHYL-BENZOOXAZOLE-4-YLamine;MFCD10703514;AKOS006283264;TS-02164;CS-0317743

Suppliers and Price of 2-Ethyl-1,3-benzoxazol-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-Amino-2-ethyl-1,3-benzoxazole
1 g
$ 256.00

Matrix Scientific
2-Ethyl-1,3-benzoxazol-4-amine 97%
1g
$ 414.00

Apolloscientific
4-Amino-2-ethyl-1,3-benzoxazole
1g
$ 232.00

American Custom Chemicals Corporation
2-ETHYL-1,3-BENZOXAZOL-4-AMINE 95.00%
1G
$ 832.18

Alichem
4-Amino-2-ethylbenzo[d]oxazole
1g
$ 4498.14

AK Scientific
2-Ethyl-1,3-benzoxazol-4-amine
5g
$ 1231.00

AK Scientific
2-Ethyl-1,3-benzoxazol-4-amine
1g
$ 394.00

Advanced Chemicals Intermediatesced Chemicals Intermediates
2-Ethyl-benzooxazol-4-ylamine 95%+
1g
$ 717.75

Acints
2-Ethyl-benzooxazol-4-ylamine 95%+
5g
$ 2167.75

Acints
2-Ethyl-benzooxazol-4-ylamine 95%+
1g
$ 717.75

Total 3 raw suppliers

Chemical Property of 2-Ethyl-1,3-benzoxazol-4-amine

Chemical Property:

PSA：52.05000
LogP:2.55360
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:162.079312947
Heavy Atom Count:12
Complexity:163

Purity/Quality:

99%, ^*data from raw suppliers

4-Amino-2-ethyl-1,3-benzoxazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=NC2=C(C=CC=C2O1)N

Technology Process of 2-Ethyl-1,3-benzoxazol-4-amine

There total 2 articles about 2-Ethyl-1,3-benzoxazol-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 477603-34-2
2-ethyl-4-nitrobenzo[d]oxazole

: 477603-35-3
4-amino-2-ethylbenzoxazole

Guidance literature:: With hydrogen; palladium(II) hydroxide; In methanol; at 20 ℃; for 120h;

Reference yield:

: 603-85-0
2-Amino-3-nitrophenol

: 477603-35-3
4-amino-2-ethylbenzoxazole

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / PTSA / 2 h / 110 °C

2: 93 percent / H₂ / Pd/C / methanol

With hydrogen; toluene-4-sulfonic acid; palladium on activated charcoal; In methanol;
DOI:10.1016/j.bmcl.2005.09.030

Reference yield:

: 477603-35-3
4-amino-2-ethylbenzoxazole

: N-(2-ethyl-5-iodobenzoxazol-4-yl)-4-trifluoromethylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; N-iodo-succinimide / benzene / 120 h / 20 °C / Inert atmosphere

2: triethylamine / tetrahydrofuran / 20 °C / Inert atmosphere

With N-iodo-succinimide; acetic acid; triethylamine; In tetrahydrofuran; benzene;