1-Phenyl-2,5,8,11-tetraoxatridecan-13-yl methanesulfonate

Base Information

• Chemical Name: 1-Phenyl-2,5,8,11-tetraoxatridecan-13-yl methanesulfonate
• CAS No.: 477781-69-4
• Molecular Formula: C16H26O7S
• Molecular Weight: 362.444
• Mol file: 477781-69-4.mol

Synonyms:mesylate of tetraethylene glycol monobenzyl ether;Methanesulfonic acid 2-{2-[2-(2-benzyloxy-ethoxy)-ethoxy]-ethoxy}-ethyl ester;13-phenyl-3,6,9,12-tetraoxatridecanyl methanesulfonate;

Chemical Property of 1-Phenyl-2,5,8,11-tetraoxatridecan-13-yl methanesulfonate

Chemical Property:

• PSA: 88.67000
• LogP: 2.31000
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

1-Phenyl-2,5,8,11-tetraoxatridecan-13-ylmethanesulfonate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Phenyl-2,5,8,11-tetraoxatridecan-13-yl methanesulfonate

There total 7 articles about 1-Phenyl-2,5,8,11-tetraoxatridecan-13-yl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-phenyl-2,5,8,11-tetraoxatridecan-13-ol (86259-87-2,1201808-31-2) + methanesulfonyl chloride (124-63-0) → 1-phenyl-2,5,8,11-tetraoxatridecan-13-yl methanesulfonate (477781-69-4)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 3h; Inert atmosphere;

DOI:10.1039/c9md00185a

Reference yield: 89.0%

→ 1-phenyl-2,5,8,11-tetraoxatridecan-13-yl methanesulfonate (477781-69-4)

Guidance literature:

Reference yield:

Tetraethylene glycol (112-60-7) → 1-phenyl-2,5,8,11-tetraoxatridecan-13-yl methanesulfonate (477781-69-4)

Guidance literature:

Multi-step reaction with 2 steps

1: NaH / tetrahydrofuran / 3 h / 100 °C

2: pyridine / 20 h / 20 °C

With pyridine; sodium hydride; In tetrahydrofuran;

DOI:10.1021/jo0617464

upstream raw materials:

1-phenyl-2,5,8,11-tetraoxatridecan-13-ol

methanesulfonyl chloride

Tetraethylene glycol

benzyl chloride

Downstream raw materials:

C₁₉H₃₃NO₆

((2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethoxy)methyl)benzene

C₃₂H₃₁F₂₇O₈

(4R)-2,2-dimethyl-4-(15-phenyl-2,5,8,11,14-pentaoxapentadecyl)-1,3-dioxolane