4-(Benzyloxy)-3-(trifluoromethyl)benzaldehyde

Base Information

Chemical Name:4-(Benzyloxy)-3-(trifluoromethyl)benzaldehyde
CAS No.:477980-90-8
Molecular Formula:C15H11F3O2
Molecular Weight:280.246
Hs Code.:
DSSTox Substance ID:DTXSID80593824
Wikidata:Q82488408
Mol file:477980-90-8.mol

Synonyms:4-(BENZYLOXY)-3-(TRIFLUOROMETHYL)BENZALDEHYDE;477980-90-8;SCHEMBL3956772;DTXSID80593824;AKOS012624914;4-Benzyloxy-3-trifluoromethyl-benzaldehyde;4-phenylmethoxy-3-(trifluoromethyl)benzaldehyde;E97873

Suppliers and Price of 4-(Benzyloxy)-3-(trifluoromethyl)benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-(Benzyloxy)-3-(trifluoromethyl)benzaldehyde

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:280.07111408
Heavy Atom Count:20
Complexity:311

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=C(C=C(C=C2)C=O)C(F)(F)F

Technology Process of 4-(Benzyloxy)-3-(trifluoromethyl)benzaldehyde

There total 3 articles about 4-(Benzyloxy)-3-(trifluoromethyl)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 444-30-4
2-(trifluoromethyl)phenol

: 477980-90-8
4-(benzyloxy)-3-(trifluoromethyl)benzaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: bromine / CHCl₃ / 2.5 h / 20 °C

2: K₂CO₃ / dimethylformamide / 21 h / 20 °C

3: 26.5 g / dimethylformamide / 26 h / 130 °C

4: 82 percent / DIBAL-H / toluene / 0.25 h / -78 °C

With bromine; diisobutylaluminium hydride; potassium carbonate; In chloroform; N,N-dimethyl-formamide; toluene;
DOI:10.1246/bcsj.77.2257

Reference yield:

: 169247-46-5
4-bromo-1-phenylmethoxy-2-(trifluoromethyl)benzene

: 477980-90-8
4-(benzyloxy)-3-(trifluoromethyl)benzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 26.5 g / dimethylformamide / 26 h / 130 °C

2: 82 percent / DIBAL-H / toluene / 0.25 h / -78 °C

With diisobutylaluminium hydride; In N,N-dimethyl-formamide; toluene;
DOI:10.1246/bcsj.77.2257

Reference yield:

: 50824-04-9
4-bromo-2-(trifluoromethyl)phenol

: 477980-90-8
4-(benzyloxy)-3-(trifluoromethyl)benzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: K₂CO₃ / dimethylformamide / 21 h / 20 °C

2: 26.5 g / dimethylformamide / 26 h / 130 °C

3: 82 percent / DIBAL-H / toluene / 0.25 h / -78 °C

With diisobutylaluminium hydride; potassium carbonate; In N,N-dimethyl-formamide; toluene;
DOI:10.1246/bcsj.77.2257