1-(4-METHOXY-PHENYL)-PYRROLE-2,5-DIONE

Base Information

• Chemical Name: 1-(4-METHOXY-PHENYL)-PYRROLE-2,5-DIONE
• CAS No.: 1081-17-0
• Molecular Formula: C11H9NO3
• Molecular Weight: 203.197
• Hs Code.: 2925190090
• Mol file: 1081-17-0.mol

Synonyms:N-p-Anisylmaleimide;NSC 39727;N-(4-Methoxyphenyl)maleimide;N-(p-Methoxyphenyl)maleimide;Maleimide,N-(p-methoxyphenyl)- (6CI,7CI,8CI);

Chemical Property of 1-(4-METHOXY-PHENYL)-PYRROLE-2,5-DIONE

Chemical Property:

• Vapor Pressure: 2.1E-05mmHg at 25°C
• Melting Point: 145-146 °C
• Refractive Index: 1.603
• Boiling Point: 361.2 °C at 760 mmHg
• PKA: -0.08±0.20(Predicted)
• Flash Point: 172.3 °C
• PSA: 46.61000
• Density: 1.317 g/cm³
• LogP: 1.18960
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-(4-Methoxyphenyl)-1H-pyrrole-2,5-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(4-METHOXY-PHENYL)-PYRROLE-2,5-DIONE

There total 16 articles about 1-(4-METHOXY-PHENYL)-PYRROLE-2,5-DIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

N-(4-methoxyphenyl)maleamic acid (24870-10-8) → N-(4-methoxyphenyl)maleimide (1081-17-0)

Guidance literature:

With sodium acetate; acetic anhydride; In diethyl ether; at 95 - 100 ℃; for 1.5h;

DOI:10.1080/10426509308034412

Reference yield: 92.0%

maleic anhydride (108-31-6) + 4-methoxy-aniline (104-94-9) → N-(4-methoxyphenyl)maleimide (1081-17-0)

Guidance literature:

With acetic acid; for 16h; Reflux;

DOI:10.1002/ejoc.202001593

Reference yield: 85.0%

maleic acid mono(4-methoxyphenyl)amide (24870-10-8,37904-20-4,37902-60-6) → N-(4-methoxyphenyl)maleimide (1081-17-0)

Guidance literature:

With tetrabutylammomium bromide; sodium carbonate; dimethyl sulfate; In water; 1,2-dichloro-ethane; at 20 ℃; for 10h;

upstream raw materials:

maleic acid mono(4-methoxyphenyl)amide

maleic anhydride

4-methoxy-aniline

methanol

Downstream raw materials:

3-chloro-1-(4-methoxyphenyl)succinimide

2-(2-amino-4-methyl-7-oxo-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-6-yl)-N-(4-methoxy-phenyl)-acetamide

4,7-bis-benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1,3,9-trioxo-2,3,3a,4,5,6,7,8,9,9b-decahydro-1H-benzo[e]isoindole-8-carboxylic acid ethyl ester

2-(4-methoxy-phenyl)-4,9-diphenyl-3a,4,9,9a-tetrahydro-4,9-epioxido-benzo[f]isoindole-1,3-dione