N-(1-(3-(2-(4-Fluorophenyl)-1,3-dioxolan-2-yl)propyl)piperidin-4-yl)benzene-1,4-diamine

Base Information

Chemical Name:N-(1-(3-(2-(4-Fluorophenyl)-1,3-dioxolan-2-yl)propyl)piperidin-4-yl)benzene-1,4-diamine
CAS No.:57718-48-6
Molecular Formula:C23H30 F N3 O2
Molecular Weight:399.509
Hs Code.:
European Community (EC) Number:260-917-9
DSSTox Substance ID:DTXSID60206425
Wikidata:Q83080256
Mol file:57718-48-6.mol

Synonyms:57718-48-6;N-(1-(3-(2-(4-Fluorophenyl)-1,3-dioxolan-2-yl)propyl)piperidin-4-yl)benzene-1,4-diamine;N-[1-[3-[2-(4-FLUOROPHENYL)-1,3-DIOXOLAN-2-YL]PROPYL]PIPERIDIN-4-YL]BENZENE-1,4-DIAMINE;n-(1-{3-[2-(4-fluorophenyl)-1,3-dioxolan-2-yl]propyl}piperidin-4-yl)benzene-1,4-diamine;EINECS 260-917-9;DTXSID60206425;A832331;N4-[1-[3-[2-(4-fluorophenyl)-1,3-dioxolan-2-yl]propyl]-4-piperidinyl]benzene-1,4-diamine;N4-[1-[3-[2-(4-fluorophenyl)-1,3-dioxolan-2-yl]propyl]piperidin-4-yl]benzene-1,4-diamine

Suppliers and Price of N-(1-(3-(2-(4-Fluorophenyl)-1,3-dioxolan-2-yl)propyl)piperidin-4-yl)benzene-1,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of N-(1-(3-(2-(4-Fluorophenyl)-1,3-dioxolan-2-yl)propyl)piperidin-4-yl)benzene-1,4-diamine

Chemical Property:

Vapor Pressure:2.53E-12mmHg at 25°C
Boiling Point:554.2°C at 760 mmHg
Flash Point:289°C
PSA：59.75000
Density:1.201g/cm³
LogP:4.55630
XLogP3:3.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:399.23220537
Heavy Atom Count:29
Complexity:479

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1NC2=CC=C(C=C2)N)CCCC3(OCCO3)C4=CC=C(C=C4)F

Technology Process of N-(1-(3-(2-(4-Fluorophenyl)-1,3-dioxolan-2-yl)propyl)piperidin-4-yl)benzene-1,4-diamine

There total 7 articles about N-(1-(3-(2-(4-Fluorophenyl)-1,3-dioxolan-2-yl)propyl)piperidin-4-yl)benzene-1,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 57718-44-2
4-(2-nitroanilino)piperidine

: 3308-94-9
4-chloro-1-(4-fluorophenyl)-1,1-(ethylenedioxy)butane

: 71-36-3
butan-1-ol

: 57718-48-6
N-(1-{3-[2-(4-fluorophenyl)-1,3-dioxolan-2-yl]propyl}piperidin-4-yl)benzene-1,4-diamine

: 60703-66-4
1-{3-[2-(4-fluorophenyl)-1,3-dioxolan-2-yl]propyl}-N-(2-nitrophenyl)piperidin-4-amine

Guidance literature:: With potassium iodide; sodium carbonate; In ethanol; chloroform; benzene;

Reference yield:

: 65053-26-1
N-γ-pyridyl-o-phenylenediamine

: 57718-48-6
N-(1-{3-[2-(4-fluorophenyl)-1,3-dioxolan-2-yl]propyl}piperidin-4-yl)benzene-1,4-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 77.4 percent / xylene / 13 h / Heating

2: NaBH₄ / 2.5 h

With sodium tetrahydroborate; In xylene;
DOI:10.1248/cpb.30.719

Reference yield:

: 7379-35-3
4-chlorpyridine hydrochloride

: 57718-48-6
N-(1-{3-[2-(4-fluorophenyl)-1,3-dioxolan-2-yl]propyl}piperidin-4-yl)benzene-1,4-diamine

Guidance literature:: Multi-step reaction with 3 steps

2: 77.4 percent / xylene / 13 h / Heating

3: NaBH₄ / 2.5 h

With sodium tetrahydroborate; In xylene;
DOI:10.1248/cpb.30.719