Diazene, (4-chlorophenyl)[(4-methylphenyl)sulfonyl]-

Base Information

• Chemical Name: Diazene, (4-chlorophenyl)[(4-methylphenyl)sulfonyl]-
• CAS No.: 4830-74-4
• Molecular Formula: C13H11ClN2O2S
• Molecular Weight: 294.762
• DSSTox Substance ID: DTXSID50455182
• Nikkaji Number: J3.638.646K
• Mol file: 4830-74-4.mol

Synonyms:4830-74-4;Diazene, (4-chlorophenyl)[(4-methylphenyl)sulfonyl]-;DTXSID50455182;1-(4-Chlorophenyl)-2-tosyldiazene;J3.638.646K

Chemical Property of Diazene, (4-chlorophenyl)[(4-methylphenyl)sulfonyl]-

Chemical Property:

• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 294.0229765
• Heavy Atom Count: 19
• Complexity: 403

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)N=NC2=CC=C(C=C2)Cl

Technology Process of Diazene, (4-chlorophenyl)[(4-methylphenyl)sulfonyl]-

There total 8 articles about Diazene, (4-chlorophenyl)[(4-methylphenyl)sulfonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-chloro-aniline (106-47-8) + (p-tolylsulfonylimino)-2,4,6-trimethylphenyliodinane → (4-chlorophenyl)azo 4-methylphenyl sulfone (4830-74-4)

Guidance literature:

With bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; In dichloromethane; at 0 ℃; for 1h; Molecular sieve; Inert atmosphere;

DOI:10.1002/ejoc.201601627

Reference yield: 90.0%

N-4-chlorophenylhydrazine (1073-69-4) + p-toluenesulfonyl chloride (98-59-9) → (4-chlorophenyl)azo 4-methylphenyl sulfone (4830-74-4)

Guidance literature:

With copper(ll) sulfate pentahydrate; potassium carbonate; In dichloromethane; at 20 ℃;

DOI:10.1039/c5nj01760b

Reference yield:

N’-(p-chlorophenyl) p-toluenesulfonyl hydrazide (56049-46-8) → (4-chlorophenyl)azo 4-methylphenyl sulfone (4830-74-4)

Guidance literature:

With potassium carbonate; copper(II) sulfate; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1021/acs.orglett.9b00540

upstream raw materials:

2-Acetoxy-2-p-tolylsulfonyl-1-phenyl-aethanon-⁽¹⁾, Acetoxy-p-tolylsulfonyl-benzoylmethan

p-chlorobenzenediazonium chloride

p-chlorobenzenediazonium tetrafluoroborate

sodium 4-methylbenzenesulfinate

Downstream raw materials:

2-(2-(4-chlorophenyl)hydrazono)-1,3-diphenylpropane-1,3-dione

ethyl 1-(4-chlorophenyl)-1H-pyrazole-4-carboxylate