3-(Thiophen-2-yl)prop-2-ynoic acid

Base Information

Chemical Name:3-(Thiophen-2-yl)prop-2-ynoic acid
CAS No.:4843-44-1
Molecular Formula:C7H4O2S
Molecular Weight:152.174
Hs Code.:
European Community (EC) Number:835-340-6
DSSTox Substance ID:DTXSID501305430
Nikkaji Number:J1.237.321J
Mol file:4843-44-1.mol

Synonyms:3-(Thiophen-2-yl)prop-2-ynoic acid;4843-44-1;3-thiophen-2-ylprop-2-ynoic Acid;3-(2-thienyl)-2-propynoic acid;3-(thiophen-2-yl)propiolic acid;Thiophen-2-yl-propynoic acid;SCHEMBL3946468;DTXSID501305430;3-thiophen-2-yl-prop-2-ynoic acid;3-(Thiophen-2-yl)prop-2-ynoicacid;MFCD11934376;AKOS012951795;EN300-248249;F88312

Suppliers and Price of 3-(Thiophen-2-yl)prop-2-ynoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(thiophen-2-yl)prop-2-ynoicacid
100mg
$ 220.00

TRC
3-(thiophen-2-yl)prop-2-ynoicacid
50mg
$ 155.00

Rieke Metals
Thiophen-2-yl-propynoicacid
1g
$ 661.00

Rieke Metals
Thiophen-2-yl-propynoicacid
5g
$ 1728.00

AK Scientific
3-(Thiophen-2-yl)prop-2-ynoicacid
5g
$ 1772.00

AK Scientific
3-(Thiophen-2-yl)prop-2-ynoicacid
1g
$ 676.00

AK Scientific
3-(Thiophen-2-yl)prop-2-ynoicacid
500mg
$ 532.00

AK Scientific
3-(Thiophen-2-yl)prop-2-ynoicacid
250mg
$ 332.00

Total 12 raw suppliers

Chemical Property of 3-(Thiophen-2-yl)prop-2-ynoic acid

Chemical Property:

PSA：65.54000
LogP:1.18420
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:151.99320054
Heavy Atom Count:10
Complexity:198

Purity/Quality:

99% ^*data from raw suppliers

3-(thiophen-2-yl)prop-2-ynoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CSC(=C1)C#CC(=O)O

Technology Process of 3-(Thiophen-2-yl)prop-2-ynoic acid

There total 19 articles about 3-(Thiophen-2-yl)prop-2-ynoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 4298-52-6
2-ethynyl-thiophene

: 124-38-9,18923-20-1
carbon dioxide

: 4843-44-1
(2-thienyl)propiolic acid

Guidance literature:: 2-ethynyl-thiophene; carbon dioxide; With diethoxymethylane; potassium tert-butylate; at 40 ℃; for 2h; Schlenk technique;

With hydrogenchloride; In water; Schlenk technique;
DOI:10.1007/s11426-017-9163-2

Reference yield: 95.0%

: 4843-44-1
(2-thienyl)propiolic acid

Guidance literature:: With diethoxymethylane; potassium tert-butylate; at 40 ℃; for 2h; Glovebox; Schlenk technique; Green chemistry;

Reference yield: 94.0%

: 124-38-9,18923-20-1
carbon dioxide

: 40231-03-6
2-(trimethylsilylethynyl)thiophene

: 4843-44-1
(2-thienyl)propiolic acid

Guidance literature:: carbon dioxide; 2-(trimethylsilylethynyl)thiophene; With cesium fluoride; In dimethyl sulfoxide; at 20 ℃; for 3h; Schlenk technique;

With hydrogenchloride; In water; at 0 ℃; pH=> 1;
DOI:10.1039/c3ob40760h