Methylenebis(phenylphosphinic acid)

Base Information

• Chemical Name: Methylenebis(phenylphosphinic acid)
• CAS No.: 4851-69-8
• Molecular Formula: C13H14O4P2
• Molecular Weight: 296.199
• DSSTox Substance ID: DTXSID90355192
• Nikkaji Number: J1.892.085I
• Wikidata: Q82133924
• Mol file: 4851-69-8.mol

Synonyms:CBMicro_000173;Methylenebis(phenylphosphinic acid);4851-69-8;Oprea1_373647;SCHEMBL17488976;DTXSID90355192;SMSF0005470;CB01331;BIM-0000013.P001

Chemical Property of Methylenebis(phenylphosphinic acid)

Chemical Property:

• XLogP3: 0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 296.03673292
• Heavy Atom Count: 19
• Complexity: 348

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)P(=O)(CP(=O)(C2=CC=CC=C2)O)O

Technology Process of Methylenebis(phenylphosphinic acid)

There total 4 articles about Methylenebis(phenylphosphinic acid) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

((phenyl)(EtO))2methylenediphosphine → P,P'-diphenyl-methylenediphosphinic acid (4851-69-8)

Guidance literature:

With hydrogenchloride; for 4.5h; Heating;

DOI:10.1007/BF02494893

Reference yield:

diethyl phenylphosphonite (1638-86-4) → P,P'-diphenyl-methylenediphosphinic acid (4851-69-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 54.5 percent

2: 85 percent / conc. HCl / 4.5 h / Heating

With hydrogenchloride; 1: Substitution / 2: Hydrolysis;

DOI:10.1007/BF02494893

Reference yield:

Ethyl phenyl(chloromethyl)phosphinate (183114-38-7) → P,P'-diphenyl-methylenediphosphinic acid (4851-69-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 54.5 percent

2: 85 percent / conc. HCl / 4.5 h / Heating

With hydrogenchloride; 1: Substitution / 2: Hydrolysis;

DOI:10.1007/BF02494893

upstream raw materials:

diethyl phenylphosphonite

Ethyl phenyl(chloromethyl)phosphinate

Downstream raw materials:

[Cu(P,P'-diphenylmethylenediphosphinate)(H₂O)]

[Cu(p,p'-diphenylmethylenediphosphinate)]

vanadyl P,P'-diphenylmethylenediphosphinate

[Sn(p,p'-diphenylmethylenediphosphinate)]