Diethyl phenylphosphonite

Base Information

• Chemical Name: Diethyl phenylphosphonite
• CAS No.: 1638-86-4
• Molecular Formula: C10H15O2P
• Molecular Weight: 198.202
• Hs Code.: 29199000
• European Community (EC) Number: 216-676-7
• NSC Number: 91794
• DSSTox Substance ID: DTXSID8061840
• Nikkaji Number: J195.273K
• Wikidata: Q81989702
• Mol file: 1638-86-4.mol

Synonyms:Diethyl phenylphosphonite;1638-86-4;diethoxy(phenyl)phosphane;Diethoxyphenylphosphine;Phosphonous acid, phenyl-, diethyl ester;Diethylphenylphosphonite;Diethyl benzenephosphonite;Phosphonous acid, P-phenyl-, diethyl ester;EINECS 216-676-7;AI3-23086;EC 216-676-7;Diethyl phenyl-phosphonite;Diethyl phenylphophonite;Diethyloxalacetatesodium salt;SCHEMBL911476;Phosphonous acid, diethyl ester;DTXSID8061840;C10H15O2P;RVDJLKVICMLVJQ-UHFFFAOYSA-;NSC91794;phenylphosphonous acid diethyl ester;MFCD00009086;NSC 91794;NSC-91794;phenyl-phosphonous acid diethyl ester;AKOS015914814;CS-0181831;D5593;FT-0624801;D90412;A810523;J-010100;N1,N1,N2,N2-tetrafluoro-2-methyl-propane-1,2-diamine

Chemical Property of Diethyl phenylphosphonite

Chemical Property:

• Vapor Pressure: 0.0784mmHg at 25°C
• Refractive Index: n20/D 1.51(lit.)
• Boiling Point: 235 °C at 760 mmHg
• Flash Point: 113 °C
• PSA: 32.05000
• Density: 1.032 g/mL at 25 °C(lit.)
• LogP: 2.69680
• Storage Temp.: 0-6°C
• Sensitive.: Air Sensitive
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 198.08096671
• Heavy Atom Count: 13
• Complexity: 118

Purity/Quality:

99.9% ^*data from raw suppliers

Diethyl Phenylphosphonite ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Phosphite Compounds
• Canonical SMILES: CCOP(C1=CC=CC=C1)OCC
• Uses: Diethyl phenylphosphonite is an aromatic compound with catalytic and antibacterial applications.

Technology Process of Diethyl phenylphosphonite

There total 24 articles about Diethyl phenylphosphonite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.5%

ethanol (64-17-5) + Dichlorophenylphosphine (644-97-3) → diethyl phenylphosphonite (1638-86-4)

Guidance literature:

With N,N-dimethyl-aniline; In pentane; for 0.5h; Ambient temperature;

DOI:10.1016/0022-1139(93)02990-V

Reference yield: 74.0%

bromobenzene (108-86-1,52753-63-6) + triethyl phosphite (122-52-1) → diethyl phenylphosphonite (1638-86-4)

Guidance literature:

bromobenzene; With magnesium; Inert atmosphere; Schlenk technique;

triethyl phosphite; In tetrahydrofuran; at 0 - 65 ℃; for 2h; Inert atmosphere; Schlenk technique;

DOI:10.1002/ejic.201800343

Reference yield: 62.0%

ethanol (64-17-5) + Phenylphosphonigsaeure-monoaethylester-monodiaethylamid (72508-61-3) → diethyl phenylphosphonite (1638-86-4)

Guidance literature:

In benzene; for 1.5h; Heating;

upstream raw materials:

diethyl phosphorylchloridite

ethanol

Dichlorophenylphosphine

sodium ethanolate

Downstream raw materials:

O-ethyl-S-methyl phenylphosphonothioate

Cyan-phenylphosphinsaeure-ethylester

O,S-diethyl phenylphosphonothionate

propiononitrile

Refernces

• 1、 Coskran,K.J. et al.. "-". . p. 5437 - 5442. Retrieved 1968.
• 2、 Ogata et al.. "-". . p. 2223. Retrieved 1972.
• 3、 Bagi, Péter,Fogassy, Elemér,Herbay, Réka,Holczbauer, Tamás,Keglevich, Gy?rgy,Mátrav?lgyi, Béla,Madarász, János,Székely, Gy?rgy,Varga, Bence. "Scalable Enantiomeric Separation of Dialkyl-Arylphosphine Oxides Based on Host–Guest Complexation with TADDOL-Derivatives, and their Recovery". supporting information. . Retrieved 2020/03/23.
• 4、 -. "New preparation method of first-class phenyl phosphine oxide initiator". Paragraph 0049-0051. . Retrieved 2020/03/05.