Dibenzothiophene, 4-(4-methoxy-2-oxiranylphenyl)-

Base Information

• Chemical Name: Dibenzothiophene, 4-(4-methoxy-2-oxiranylphenyl)-
• CAS No.: 485824-12-2
• Molecular Formula: C21H16O2S
• Molecular Weight: 332.423
• Mol file: 485824-12-2.mol

Synonyms:

Chemical Property of Dibenzothiophene, 4-(4-methoxy-2-oxiranylphenyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Dibenzothiophene, 4-(4-methoxy-2-oxiranylphenyl)-

There total 3 articles about Dibenzothiophene, 4-(4-methoxy-2-oxiranylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

trimethylsulphonium iodide (2181-42-2) + 4-(2-formyl-4-methoxyphenyl)dibenzothiophene (485824-06-4) → 4-(2-epoxyethyl-4-methoxyphenyl)dibenzothiophene (485824-12-2)

Guidance literature:

With potassium hydroxide; In acetonitrile; at 65 - 70 ℃; for 20h;

DOI:10.1021/jo020493l

Reference yield:

4-dibenzothiophene boronic acid (108847-20-7) → 4-(2-epoxyethyl-4-methoxyphenyl)dibenzothiophene (485824-12-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / Pd(PPh₃)4; CsF / 1,2-dimethoxy-ethane / 20 h / Heating

2: 100 percent / KOH / acetonitrile / 20 h / 65 - 70 °C

With potassium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; cesium fluoride; In 1,2-dimethoxyethane; acetonitrile; 1: Suzuki coupling reaction;

DOI:10.1021/jo020493l

Reference yield:

2-bromo-5-methoxy-benzaldehyde (7507-86-0) → 4-(2-epoxyethyl-4-methoxyphenyl)dibenzothiophene (485824-12-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / Pd(PPh₃)4; CsF / 1,2-dimethoxy-ethane / 20 h / Heating

2: 100 percent / KOH / acetonitrile / 20 h / 65 - 70 °C

With potassium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; cesium fluoride; In 1,2-dimethoxyethane; acetonitrile; 1: Suzuki coupling reaction;

DOI:10.1021/jo020493l

upstream raw materials:

trimethylsulphonium iodide

4-(2-formyl-4-methoxyphenyl)dibenzothiophene

4-dibenzothiophene boronic acid

2-bromo-5-methoxy-benzaldehyde

Refernces