4-Bromomethcathinone

Base Information

• Chemical Name: 4-Bromomethcathinone
• CAS No.: 486459-03-4
• Molecular Formula: C10H12BrNO
• Molecular Weight: 242.00
• UNII: 9GU9FVS6HH
• DSSTox Substance ID: DTXSID401014169
• Nikkaji Number: J3.114.082J
• Wikipedia: 4-Bromomethcathinone
• Wikidata: Q4637105
• Mol file: 486459-03-4.mol

Synonyms:4-Bromomethcathinone;Brephedrone;9GU9FVS6HH;486459-03-4;1-(4-BROMOPHENYL)-2-(METHYLAMINO)-1-PROPANONE;UNII-9GU9FVS6HH;1-(4-bromophenyl)-2-(methylamino)propan-1-one;1-Propanone, 1-(4-bromophenyl)-2-(methylamino)-;4-BMC;SCHEMBL20481912;DTXSID401014169;AKOS022330106;4'-Bromo-alpha-(methylamino)propiophenone;PD045200;Q4637105

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Chemical Property of 4-Bromomethcathinone

Chemical Property:

• Boiling Point: 321.891 °C at 760 mmHg
• Flash Point: 148.474 °C
• Density: 1.35 g/cm³
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 241.01023
• Heavy Atom Count: 13
• Complexity: 176

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)C1=CC=C(C=C1)Br)NC

Technology Process of 4-Bromomethcathinone

There total 3 articles about 4-Bromomethcathinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4'-Bromopropiophenone (10342-83-3) → 4‐bromomethcathinone (486459-03-4)

Guidance literature:

Multi-step reaction with 2 steps

1: bromine / dichloromethane

2: dichloromethane / 12 h

With bromine; In dichloromethane;

DOI:10.3390/ijms20071524

Reference yield:

bromobenzene (108-86-1,52753-63-6) → 4‐bromomethcathinone (486459-03-4)

Guidance literature:

Multi-step reaction with 3 steps

1: aluminum (III) chloride / dichloromethane

2: bromine / dichloromethane

3: dichloromethane / 12 h

With aluminum (III) chloride; bromine; In dichloromethane; 1: |Friedel-Crafts Acylation;

DOI:10.3390/ijms20071524

Reference yield:

methylamine (74-89-5) + 2-bromo-1-(4-bromophenyl)propan-1-one (38786-67-3) → 4‐bromomethcathinone (486459-03-4)

Guidance literature:

In dichloromethane; for 12h;

DOI:10.3390/ijms20071524

upstream raw materials:

methylamine

2-bromo-1-(4-bromophenyl)propan-1-one

4'-Bromopropiophenone

bromobenzene

Downstream raw materials:

4-bromomethcathinone

4-bromomethcathinone

Refernces