1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid

Base Information

Chemical Name:1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid
CAS No.:4869-45-8
Molecular Formula:C7H8N2O4
Molecular Weight:184.14900
Hs Code.:2933599090
European Community (EC) Number:892-226-9
DSSTox Substance ID:DTXSID30516568
Wikidata:Q82378044
Mol file:4869-45-8.mol

Synonyms:4869-45-8;1,3-DIMETHYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLIC ACID;1,3-dimethyl-2,4-dioxopyrimidine-5-carboxylic acid;MFCD09901808;5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-;SCHEMBL11720340;DTXSID30516568;AMY20045;1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylicAcid;AKOS005139323;SB57281;BS-11745;SY019886;CS-0072140;FT-0761192;EN300-79497;F2113-0333;Z385370184;1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylic acid;1 pound not3-Dimethyl-2 pound not4-dioxo-1 pound not2 pound not3 pound not4-tetrahydropyrimidine-5-carboxylic Acid

Suppliers and Price of 1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylicacid 95%+
100mg
$ 100.00

Matrix Scientific
1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylicacid 95%+
500mg
$ 288.00

Matrix Scientific
1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylicacid 95%+
2.500g
$ 1048.00

Crysdot
1,3-DIMETHYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLICACID 95+%
10g
$ 453.00

Chemenu
1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylicacid 95%
10g
$ 424.00

American Custom Chemicals Corporation
1,3-DIMETHYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLIC ACID 95.00%
5MG
$ 503.65

Ambeed
1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylicacid 98%
1g
$ 62.00

Ambeed
1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylicacid 98%
250mg
$ 28.00

Ambeed
1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylicacid 98%
100mg
$ 20.00

Ambeed
1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylicacid 98%
5g
$ 186.00

Total 14 raw suppliers

Chemical Property of 1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid

Chemical Property:

Melting Point:193-194 °C
Boiling Point:308.0±52.0 °C(Predicted)
PKA:5.28±0.20(Predicted)
PSA：81.30000
Density:1.472±0.06 g/cm3(Predicted)
LogP:-1.21780
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:184.04840674
Heavy Atom Count:13
Complexity:321

Purity/Quality:

99%, ^*data from raw suppliers

1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylicacid 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C=C(C(=O)N(C1=O)C)C(=O)O
Uses 1,3-Dimethyl-5-carboxyuracil is used in the synthesis and SAR of drug-like allosteric inhibitors of a mammalian lectin.

Technology Process of 1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid

There total 14 articles about 1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 874-14-6,156398-76-4
1,3-dimethyluracil

: 201230-82-2
carbon monoxide

: 4869-45-8
1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid

Guidance literature:: With sodium persulfate; palladium diacetate; In acetic acid; for 7h; Heating;
DOI:10.1246/cl.1983.127

Reference yield: 60.0%

: 28485-17-8
5-carbethoxyuracil

: 74-88-4
methyl iodide

: 4869-45-8
1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid

Guidance literature:: 5-carbethoxyuracil; methyl iodide; With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 18h;

With lithium hydroxide; In tetrahydrofuran; methanol; at 60 ℃; for 4h;