3-Phenyl-2-isoxazoline-5-carboxylic acid

Base Information

Chemical Name:3-Phenyl-2-isoxazoline-5-carboxylic acid
CAS No.:4872-58-6
Molecular Formula:C10H9NO3
Molecular Weight:191.186
Hs Code.:2934999090
Mol file:4872-58-6.mol

Synonyms:3-phenyl-4,5-dihydro-isoxazole-5-carboxylic acid;rac-3-phenyl-2-isoxazoline-5-carboxylic acid;3-Phenyl-4,5-dihydro-isoxazol-5-carbonsaeure;

Suppliers and Price of 3-Phenyl-2-isoxazoline-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-phenyl-4,5-dihydroisoxazole-5-carboxylicAcid
25mg
$ 65.00

Matrix Scientific
3-Phenyl-4,5-dihydro-isoxazole-5-carboxylic acid
500mg
$ 220.00

Matrix Scientific
3-Phenyl-4,5-dihydro-isoxazole-5-carboxylic acid
1g
$ 339.00

Crysdot
3-Phenyl-4,5-dihydroisoxazole-5-carboxylicacid 97%
1g
$ 320.00

Crysdot
3-Phenyl-4,5-dihydroisoxazole-5-carboxylicacid 97%
5g
$ 904.00

AK Scientific
3-Phenyl-4,5-dihydro-isoxazole-5-carboxylicacid
250mg
$ 465.00

Total 8 raw suppliers

Chemical Property of 3-Phenyl-2-isoxazoline-5-carboxylic acid

Chemical Property:

Melting Point:143-144 °C
Boiling Point:364.7±52.0 °C(Predicted)
PKA:2.76±0.40(Predicted)
PSA：58.89000
Density:1.34±0.1 g/cm3(Predicted)
LogP:0.69980

Purity/Quality:

98%min ^*data from raw suppliers

3-phenyl-4,5-dihydroisoxazole-5-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Phenyl-2-isoxazoline-5-carboxylic acid

There total 28 articles about 3-Phenyl-2-isoxazoline-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 50899-14-4
(+/-)-ethyl 3-phenyl-4,5-dihydroisoxazole-5-carboxylate

: 4872-58-6
3-phenyl-4,5-dihydroisoxazole-5-carboxylic acid

Guidance literature:: With sodium hydroxide; In ethanol; Heating;
DOI:10.1002/jhet.5570430240

Reference yield: 84.0%

: 1011-38-7
4,5-dihydro-3-phenyl-5-isoxazolecarbonitrile

: 4872-58-6
3-phenyl-4,5-dihydroisoxazole-5-carboxylic acid

Guidance literature:: With hydrogenchloride; In water; at 100 ℃; for 10h; Sealed tube;
DOI:10.1002/ejoc.201701651

Reference yield: 67.0%

: 873-67-6
benzonitrile oxide

: 79-10-7
acrylic acid

: 4872-58-6
3-phenyl-4,5-dihydroisoxazole-5-carboxylic acid

Guidance literature:: With 2-nitrophenylboronic acid; In 1,2-dichloro-ethane; at 25 ℃; for 24h; regioselective reaction; Inert atmosphere;
DOI:10.1002/chem.200903484