10.1016/j.tetlet.2007.11.050
The research focuses on the construction of the 3-prenyl-4-oxa-tricyclo[4.3.1.03,7]dec-8-en-2-one core, which is a key structural component found in caged xanthonoid natural products derived from Garcinia plants. The purpose of the study was to develop a two-step protocol utilizing tandem Wessely oxidation and intramolecular Diels–Alder reaction to access this core structure efficiently. The researchers successfully demonstrated the generality of this method through various examples, showing that the prenyl group could be installed in the required position. They also showed that these tricyclic scaffolds could be further transformed into substituted c-lactones through a photochemical 1,3-acyl shift and decarbonylation. Key chemicals used in the process include lead tetraacetate (LTA), acrylic acid, and various prenylated and oxygenated aromatic precursors. The study concluded that this two-step sequence is a versatile method for accessing the caged tricyclic system present in Garcinia xanthonoids and that the synthesized 4-oxa-tricyclo[4.3.1.03,7]dec-8-en-2-ones are valuable precursors for synthetically useful c-lactones.
10.1021/jo01375a001
The study focuses on the synthesis and characterization of neopentyl esters of acrylic and methacrylic acids. Neopentyl alcohol, a key reactant, was prepared using two methods: the Whitmore method involving tert-butylmagnesium chloride and pivalyl chloride, and the more practical lithium aluminum hydride reduction of pivalic acid. Neopentyl acrylate was synthesized from neopentyl alcohol and either acryloyl chloride or acrylic acid, while neopentyl methacrylate was prepared from neopentyl alcohol and either methacryloyl chloride or methacrylic acid. The esters' physical properties were measured and reported. The study also highlighted the partly hindered character of neopentyl methacrylate, which affected its saponification process.
10.1007/s11243-012-9635-y
The research focuses on the synthesis, characterization, and catalytic activity of three palladium(II) complexes containing Schiff base ligands. The purpose of this study was to create new Pd(II) complexes that could serve as heterogeneous catalysts in organic reactions, specifically in the Heck coupling reaction of bromobenzene with acrylic acid. The researchers synthesized three new Pd(II) complexes: [Pd4(L1)4] (1), [Pd2(L2)2Cl2] (2), and [Pd(L3)2Cl2] (3), using solvothermal methods. The Schiff base ligands, HL1, L2, and L3, were prepared by condensation reactions involving benzaldehyde or 2,4-dichlorobenzaldehyde with aromatic amines. The palladium complexes were then formed by reacting PdCl2 with these ligands under solvothermal conditions. The study concluded that these complexes show moderate catalytic activity in the Heck coupling reaction, and their effectiveness is sensitive to the choice of base and solvent. The chemicals used in the process included palladium chloride, methanol, ethanol, and various aromatic amines and aldehydes for the preparation of the Schiff base ligands, as well as bromobenzene, acrylic acid, and triethylamine for the catalytic reactions.
C, 
N
C:Corrosive;
