(S)-Proxyphylline

Base Information

Chemical Name:(S)-Proxyphylline
CAS No.:86540-95-6
Molecular Formula:C₁₀H₁₄N₄O₃
Molecular Weight:238.246
Hs Code.:
Mol file:86540-95-6.mol

Synonyms:(S)-proxyphylline;7-((S)-2-Hydroxy-propyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione;(+)-(S)-proxyphylline;

Suppliers and Price of (S)-Proxyphylline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (S)-Proxyphylline

Chemical Property:

Vapor Pressure:2.63E-10mmHg at 25°C
Boiling Point:487.2°C at 760 mmHg
Flash Point:248.5°C
PSA：82.05000
Density:1.46g/cm³
LogP:-1.18550

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-Proxyphylline

There total 10 articles about (S)-Proxyphylline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 58-55-9,75448-53-2
theophylline

: 75-56-9,16033-71-9
methyloxirane

: 603-00-9,86480-51-5,86540-95-6,86540-96-7
proxyphylline

Guidance literature:: With triethylamine; In methanol; for 4h; Reflux;
DOI:10.1021/acs.joc.5b01840

Reference yield:

: 10226-64-9
7-Acetonyltheophylline

: 603-00-9,86480-51-5,86540-95-6,86540-96-7
proxyphylline

Guidance literature:: With ethanol; nickel; at 100 - 120 ℃; under 66195.7 Torr; Hydrogenation;

Reference yield:

: 58-55-9,75448-53-2
theophylline

: 603-00-9,86480-51-5,86540-95-6,86540-96-7
proxyphylline

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) aq. NaOH / 1.) EtOH, reflux, 25 min, 2.) DMF, 60 deg C, 24 h

2: NaBH₄ / methanol; diethyl ether

With sodium hydroxide; sodium tetrahydroborate; In methanol; diethyl ether;
DOI:10.1021/jm980469t