4-Isopropyl styrene

Base Information

• Chemical Name: 4-Isopropyl styrene
• CAS No.: 2055-40-5
• Molecular Formula: C11H14
• Molecular Weight: 146.232
• Hs Code.: 2902909090
• European Community (EC) Number: 218-151-8
• DSSTox Substance ID: DTXSID40174552
• Nikkaji Number: J298.672H
• Wikidata: Q83044641
• Mol file: 2055-40-5.mol

Synonyms:4-isopropyl styrene;2055-40-5;4-Iso-propyl styrene;p-Isopropylstyrene;1-ethenyl-4-propan-2-ylbenzene;4-ISO-PROPYLSTYRENE;1-Isopropyl-4-vinylbenzene;Benzene, 1-ethenyl-4-(1-methylethyl)-;1-ethenyl-4-(propan-2-yl)benzene;EINECS 218-151-8;1-Isopropyl-4-vinyl-benzene;1-Vinyl-4-isopropylbenzene;DTXSID40174552;CAA05540;1-ethenyl-4-(1-methylethyl)benzene;MFCD00080631;AKOS006343231;BB 0221045;FT-0692519;EN300-1243690;A1-04293

Chemical Property of 4-Isopropyl styrene

Chemical Property:

• Vapor Pressure: 0.374mmHg at 25°C
• Melting Point: -44.7°C
• Refractive Index: 1.5289
• Boiling Point: 204.6°Cat760mmHg
• Flash Point: 70.1°C
• PSA: 0.00000
• Density: 0.883g/cm³
• LogP: 3.45300
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 146.109550447
• Heavy Atom Count: 11
• Complexity: 116

Purity/Quality:

99% ^*data from raw suppliers

1-Isopropyl-4-vinylbenzene 95% ^*data from reagent suppliers

Safty Information:

• Statements: 10-36/37/38
• Safety Statements: 16-26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C1=CC=C(C=C1)C=C

Technology Process of 4-Isopropyl styrene

There total 24 articles about 4-Isopropyl styrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-(4-isopropylphenyl)ethanol (1475-10-1) → 4-isopropylstyrene (2055-40-5)

Guidance literature:

potassium hydrogensulfate; at 190 ℃; under 50 Torr;

DOI:10.1016/S0040-4020(01)87687-0

Reference yield: 76.0%

cupric chloride + Diethyl tartrate (408332-88-7) → 4-isopropylstyrene (2055-40-5)

Guidance literature:

With hydrogenchloride; carbon monoxide; palladium(II) chloride; In tetrahydrofuran; water;

Reference yield: 75.0%

Methyltriphenylphosphonium bromide (1779-49-3) + (4-isopropylbenzaldehyde) (122-03-2) → 4-isopropylstyrene (2055-40-5)

Guidance literature:

Methyltriphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

(4-isopropylbenzaldehyde); In tetrahydrofuran; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1039/c6ra19190h

upstream raw materials:

1-(4-isopropylphenyl)ethanol

4-isopropylcinnamic acid

methyl magnesium iodide

(4-isopropylbenzaldehyde)

Downstream raw materials:

1-(1,2-dibromo-ethyl)-4-isopropyl-benzene

2-(4-isopropylphenyl)ethanol

Bis-[2-chloro-2-(4-isopropyl-phenyl)-ethyl]-diazene N,N'-dioxide

(1S,2S)-2-(4-Isopropyl-phenyl)-cyclopropanecarboxylic acid ethyl ester

Refernces

• 1、 Lin, Shanshan,Liu, Jianguo,Ma, Longlong,Sun, Jiangming. "In-situ facile synthesis novel N-doped thin graphene layer encapsulated Pd@N/C catalyst for semi-hydrogenation of alkynes". . . Retrieved 2021/12/03.
• 2、 Song, Di,Bi, Fangchao,Zhang, Nan,Qin, Yinhui,Liu, Xingbang,Teng, Yuetai,Ma, Shutao. "Design, synthesis of novel 4,5-dihydroisoxazole-containing benzamide derivatives as highly potent FtsZ inhibitors capable of killing a variety of MDR Staphylococcus aureus". supporting information. . Retrieved 2020/09/11.