3-Chloro-5-fluorobenzaldehyde

Base Information

Chemical Name:3-Chloro-5-fluorobenzaldehyde
CAS No.:90390-49-1
Molecular Formula:C7H4ClFO
Molecular Weight:158.56
Hs Code.:29124990
European Community (EC) Number:642-796-8
DSSTox Substance ID:DTXSID10370529
Wikidata:Q72450475
Mol file:90390-49-1.mol

Synonyms:3-Chloro-5-fluorobenzaldehyde;90390-49-1;MFCD02261734;3-Chloro-5-fluoro-benzaldehyde;Benzaldehyde, 3-chloro-5-fluoro-;SCHEMBL224110;DTXSID10370529;QWBYWPJNPKGEBO-UHFFFAOYSA-N;CS-B0666;BBL101288;STL555084;AKOS005257576;AB11796;AC-2300;PS-8803;AM20050103;C3365;FT-0642167;A21252;EN300-141431;J-512266;Z1203161793

Suppliers and Price of 3-Chloro-5-fluorobenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Chloro-5-fluorobenzaldehyde
100mg
$ 45.00

TCI Chemical
3-Chloro-5-fluorobenzaldehyde
5G
$ 198.00

TCI Chemical
3-Chloro-5-fluorobenzaldehyde
1G
$ 64.00

SynQuest Laboratories
3-Chloro-5-fluorobenzaldehyde 97%
5 g
$ 24.00

SynQuest Laboratories
3-Chloro-5-fluorobenzaldehyde 97%
1 g
$ 16.00

SynQuest Laboratories
3-Chloro-5-fluorobenzaldehyde 97%
25 g
$ 66.00

Sigma-Aldrich
3-CHLORO-5-FLUOROBENZALDEHYDE Aldrich
50mg
$ 144.00

Rieke Metals
3-Chloro-5-fluorobenzaldehyde 97%
5g
$ 132.00

Rieke Metals
3-Chloro-5-fluorobenzaldehyde 97%
25g
$ 380.00

Rieke Metals
3-Chloro-5-fluorobenzaldehyde 97%
10g
$ 190.00

Total 61 raw suppliers

Chemical Property of 3-Chloro-5-fluorobenzaldehyde

Chemical Property:

Appearance/Colour:white to yellow low melting solid or clear liquid
Vapor Pressure:0.285mmHg at 25°C
Melting Point:42 °C
Refractive Index:1.559
Boiling Point:202.9 °C at 760 mmHg
Flash Point:76.5 °C
PSA：17.07000
Density:1.352 g/cm³
LogP:2.29160
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Sensitive.:Air Sensitive
Solubility.:soluble in Methanol
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:157.9934706
Heavy Atom Count:10
Complexity:129

Purity/Quality:

98+% ^*data from raw suppliers

3-Chloro-5-fluorobenzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,T
Statements: 36/37/38-23/24/25
Safety Statements: 37/39-26-45-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C=C1F)Cl)C=O

Technology Process of 3-Chloro-5-fluorobenzaldehyde

There total 6 articles about 3-Chloro-5-fluorobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 79944-64-2
(3-chloro-5-fluorophenyl)methanol

: 90390-49-1
3-chloro-5-fluoro-benzaldehyde

Guidance literature:: With manganese(IV) oxide; In benzene; for 24h; Heating;
DOI:10.1021/jm00375a005

Reference yield:

: 71022-43-0
3,5-dinitrobenzyl alcohol

: 90390-49-1
3-chloro-5-fluoro-benzaldehyde

Guidance literature:: Multi-step reaction with 6 steps

1: 62 percent / (NH₄)2S / methanol / 5 h / Heating

2: 1.) HNO₂, 2.) CuCl₂, CuCl, 12percent aq. HCl / 1.) 0 deg C, 2.) 60 deg C, 1 h

3: 81 percent / Fe, HCl (gas) / ethanol

4: 65 percent / aq. HBF₄, NaNO₂ / -5 °C

5: 25 percent / Heating

6: 73 percent / MnO₂ / benzene / 24 h / Heating

With hydrogenchloride; manganese(IV) oxide; diammonium sulfide; tetrafluoroboric acid; cis-nitrous acid; iron; copper(l) chloride; copper dichloride; sodium nitrite; In methanol; ethanol; benzene;
DOI:10.1021/jm00375a005

Reference yield:

: 79944-62-0
(3-chloro-5-nitrophenyl)methanol

: 90390-49-1
3-chloro-5-fluoro-benzaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: 81 percent / Fe, HCl (gas) / ethanol

2: 65 percent / aq. HBF₄, NaNO₂ / -5 °C

3: 25 percent / Heating

4: 73 percent / MnO₂ / benzene / 24 h / Heating

With hydrogenchloride; manganese(IV) oxide; tetrafluoroboric acid; iron; sodium nitrite; In ethanol; benzene;
DOI:10.1021/jm00375a005