Butanedioic acid, [(1S)-1-[4-[[bis(1,1-dimethylethoxy)phosphinyl]methyl]phenyl]-2-propenyl ]-, mono(1,1-dimethylethyl) ester, (2S)-

Base Information

Chemical Name:Butanedioic acid, [(1S)-1-[4-[[bis(1,1-dimethylethoxy)phosphinyl]methyl]phenyl]-2-propenyl ]-, mono(1,1-dimethylethyl) ester, (2S)-
CAS No.:495404-40-5
Molecular Formula:C26H41O7P
Molecular Weight:496.581
Hs Code.:
Mol file:495404-40-5.mol

Synonyms:

Suppliers and Price of Butanedioic acid, [(1S)-1-[4-[[bis(1,1-dimethylethoxy)phosphinyl]methyl]phenyl]-2-propenyl ]-, mono(1,1-dimethylethyl) ester, (2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Butanedioic acid, [(1S)-1-[4-[[bis(1,1-dimethylethoxy)phosphinyl]methyl]phenyl]-2-propenyl ]-, mono(1,1-dimethylethyl) ester, (2S)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Butanedioic acid, [(1S)-1-[4-[[bis(1,1-dimethylethoxy)phosphinyl]methyl]phenyl]-2-propenyl ]-, mono(1,1-dimethylethyl) ester, (2S)-

There total 3 articles about Butanedioic acid, [(1S)-1-[4-[[bis(1,1-dimethylethoxy)phosphinyl]methyl]phenyl]-2-propenyl ]-, mono(1,1-dimethylethyl) ester, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 495404-36-9
tert-butyl 3-[((4S)-2-oxo-4-phenyl(1,3-oxazolidin-3-yl))carbonyl]-(3S,4S)-4-(4-{[bis(tert-butoxy)phosphono]methyl}phenyl)hex-5-enoate

: 495404-40-5
(2S,3S)-3-(4-{[bis(tert-butoxy)phosphono]methyl}phenyl)-2-{[(tert-butyl)oxycarbonyl]methyl}pent-4-enoic acid

Guidance literature:: With lithium hydroxide; dihydrogen peroxide; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1021/jm0203635

Reference yield:

: 5292-43-3
bromoacetic acid tert-butyl ester

: 495404-40-5
(2S,3S)-3-(4-{[bis(tert-butoxy)phosphono]methyl}phenyl)-2-{[(tert-butyl)oxycarbonyl]methyl}pent-4-enoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaHMDS / tetrahydrofuran / 0.5 h / -78 °C

1.2: 77 percent / tetrahydrofuran / 2 h / -78 °C

2.1: 85 percent / aq. H₂O₂; aq. LiOH / tetrahydrofuran / 0 - 20 °C

With lithium hydroxide; dihydrogen peroxide; sodium hexamethyldisilazane; In tetrahydrofuran;
DOI:10.1021/jm0203635

Reference yield:

: 350038-45-8
3-[(3R)-3-(4-{[bis(tert-butoxy)phosphono]methyl}phenyl)pent-4-enoyl]-(4S)-4-phenyl-1,3-oxazolidin-2-one

: 495404-40-5
(2S,3S)-3-(4-{[bis(tert-butoxy)phosphono]methyl}phenyl)-2-{[(tert-butyl)oxycarbonyl]methyl}pent-4-enoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaHMDS / tetrahydrofuran / 0.5 h / -78 °C

1.2: 77 percent / tetrahydrofuran / 2 h / -78 °C

2.1: 85 percent / aq. H₂O₂; aq. LiOH / tetrahydrofuran / 0 - 20 °C

With lithium hydroxide; dihydrogen peroxide; sodium hexamethyldisilazane; In tetrahydrofuran;
DOI:10.1021/jm0203635