(1-Methylpyrrolidin-3-yl)methanol

Base Information

• Chemical Name: (1-Methylpyrrolidin-3-yl)methanol
• CAS No.: 5021-33-0
• Molecular Formula: C6H13NO
• Molecular Weight: 115.175
• Hs Code.: 2933990090
• European Community (EC) Number: 820-181-7
• NSC Number: 165644,239753
• DSSTox Substance ID: DTXSID60304410
• Mol file: 5021-33-0.mol

Synonyms:(1-methylpyrrolidin-3-yl)methanol;5021-33-0;(1-Methyl-pyrrolidin-3-yl)-methanol;(1-Methyl-3-pyrrolidyl)methanol;MFCD08059753;1-methyl-3-pyrrolidinemethanol;MFCD17015955;MFCD17015956;3-Pyrrolidinemethanol, 1-methyl-;NSC165644;SCHEMBL731818;DTXSID60304410;NPWMWLAPRVMNBN-UHFFFAOYSA-N;(1-methyl-3-pyrrolidinyl)methanol;1-Methyl-2-hydroxymethyl-pyrrolidi;1-methyl-3-hydroxymethylpyrrolidine;BCP30736;(1-methylpyrrolidin-3-yl) methanol;(R)-1-Methylpyrrolidine-3-methanol;NSC239753;3-(Hydroxymethyl)-1-methylpyrrolidine;3-(Hydroxymethyl)-N-methylpyrrolidine;AKOS005174056;NSC-165644;NSC-239753;PB31861;PB34858;SB37369;(S)-(1-Methyl-3-pyrrolidinyl)methanol;AM803966;AS-39527;SY023473;SY098600;SY259236;CS-0005413;FT-0683688;EC-000.1843;EN300-113523;A871639;J-004446;J-503626;F2147-0775;Z976730728;3-pyrrolidinemethanol, 1-methyl- pound>>1-Methyl-3-pyrrolidinemethanol

Chemical Property of (1-Methylpyrrolidin-3-yl)methanol

Chemical Property:

• Vapor Pressure: 2.36mmHg at 25°C
• Refractive Index: 1.468
• Boiling Point: 141.7 °C at 760 mmHg
• PKA: 14.93±0.10(Predicted)
• Flash Point: 41.2 °C
• PSA: 23.47000
• Density: 0.973 g/cm³
• LogP: -0.13170
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 0
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 115.099714038
• Heavy Atom Count: 8
• Complexity: 74.9

Purity/Quality:

97% ^*data from raw suppliers

(1-Methylpyrrolidin-3-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1CCC(C1)CO

Technology Process of (1-Methylpyrrolidin-3-yl)methanol

There total 8 articles about (1-Methylpyrrolidin-3-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

trimethylamine-N-oxide (1184-78-7) + allyl alcohol (107-18-6) → (1-methyl-3-pirrolidinyl)methanol (5021-33-0,1210934-04-5)

Guidance literature:

With DAL; In tetrahydrofuran; at -78 ℃;

Reference yield:

1-methyl-pyrrolidine-3-carboxylic acid (25712-60-1,412281-11-9) → (1-methyl-3-pirrolidinyl)methanol (5021-33-0,1210934-04-5)

Guidance literature:

With hydrogenchloride; dimethylsulfide borane complex; In tetrahydrofuran; at 210 ℃; for 2h;

Reference yield:

→ (1-methyl-3-pirrolidinyl)methanol (5021-33-0,1210934-04-5)

Guidance literature:

With lithium aluminium tetrahydride; diethyl ether;

upstream raw materials:

1-(1-methyl-pyrrolidin-3-yl)-ethane-1,2-diol

trimethylamine-N-oxide

allyl alcohol

1-methyl-pyrrolidin-2-one

Downstream raw materials:

C₂₄H₂₆N₂O₅

C₂₈H₃₂N₂O₅

C₃₀H₃₄N₂O₆