1,22-Docosanediol

Base Information

• Chemical Name: 1,22-Docosanediol
• CAS No.: 22513-81-1
• Molecular Formula: C22H46 O2
• Molecular Weight: 342.6
• Hs Code.: 2905399090
• Mol file: 22513-81-1.mol

Synonyms:NSC405997; a,w-Docosanediol

Chemical Property of 1,22-Docosanediol

Chemical Property:

• Vapor Pressure: 2.62E-10mmHg at 25°C
• Melting Point: 105.3-105.5 °C
• Boiling Point: 457.8°Cat760mmHg
• PKA: 14.90±0.10(Predicted)
• Flash Point: 189.4°C
• PSA: 40.46000
• Density: 0.885g/cm³
• LogP: 6.77300

Purity/Quality:

90%, 98% ^*data from raw suppliers

Docosane-1,22-diol 98+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,22-Docosanediol

There total 2 articles about 1,22-Docosanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-[(11-bromoundecyl)oxy]tetrahydro-2H-pyran (52056-69-6) + 4,4'-bis(chloromethyl)biphenyl (1667-10-3) → docosane-1,22-diol (22513-81-1) + 2,2'-[biphenyl-4,4'-diylbis(dodecane-12,1-diyloxy)]bis(tetrahydro-2H-pyran)

Guidance literature:

2-[(11-bromoundecyl)oxy]tetrahydro-2H-pyran; With magnesium; In tetrahydrofuran; at 50 ℃; for 2h; Inert atmosphere;

4,4'-bis(chloromethyl)biphenyl; With dilithium tetrachlorocuprate; In tetrahydrofuran; at 0 ℃; for 3h; Inert atmosphere;

DOI:10.1007/s00706-012-0833-2

Reference yield:

2-[(11-bromoundecyl)oxy]tetrahydro-2H-pyran (52056-69-6) + 4-4'-bis(bromomethyl)biphenyl (20248-86-6) → docosane-1,22-diol (22513-81-1) + 2,2'-[biphenyl-4,4'-diylbis(dodecane-12,1-diyloxy)]bis(tetrahydro-2H-pyran)

Guidance literature:

2-[(11-bromoundecyl)oxy]tetrahydro-2H-pyran; With magnesium; In tetrahydrofuran; at 50 ℃; for 2h; Inert atmosphere;

4-4'-bis(bromomethyl)biphenyl; With dilithium tetrachlorocuprate; In tetrahydrofuran; at 0 ℃; for 3h; Inert atmosphere;

DOI:10.1007/s00706-012-0833-2

Reference yield: 83.0%

docosane-1,22-diol (22513-81-1) + p-toluenesulfonyl chloride (98-59-9) → docosane-1,22-diyl bis(4-methylbenzenesulfonate)

Guidance literature:

With pyridine; In chloroform; at 0 - 5 ℃; for 18.5h; Schlenk technique;

DOI:10.1002/jlcr.3885

upstream raw materials:

2-[(11-bromoundecyl)oxy]tetrahydro-2H-pyran

4,4'-bis(chloromethyl)biphenyl

4-4'-bis(bromomethyl)biphenyl

Downstream raw materials:

1,22-Bis(trimethylsiloxy)docosan

1,44-tetratetracontanediol

1,22-bis(p-formylphenoxy)docosane

1,2-bis[p-(benzyliminomethylene)phenoxy]docosane

Refernces