1667-10-3

Basic information

• Product Name: 4,4'-Bis(chloromethyl)-1,1'-biphenyl
• Synonyms: 4,4'-BIS(CHLOROMETHYL)-1,1'-BIPHENYL, 95 %;4,4'-bis(Chloromethyl)-1,1'-Bi;4,4-Dichloride-methyl-bispheny;BCMB 4,4-bis(Chloromethyl)-Biphenyl;4,4'-Bis(cnloromethyl)diphonyl;BCMP;4,4''-BIS(CHLOROMETHYL)-1,1''-BIPHENYL 95%;4,4'-bis(chloromethyl)-1,1'-biphenyl
• CAS NO: 1667-10-3
• Molecular Formula: C₁₄H₁₂Cl₂
• Molecular Weight: 251.15
• EINECS: 216-784-4
• Product Categories: Intermediates of Dyes and Pigments;Biphenyl & Diphenyl ether;Biphenyls (for High-Performance Polymer Research);Functional Materials;Reagent for High-Performance Polymer Research;Aryl;C13 to C37+;Halogenated Hydrocarbons;Biphenyl series
• Mol File: 1667-10-3.mol
• Article Data: 14

Chemical Properties

• Melting Point: 126 °C (dec.)(lit.)
• Boiling Point: 184 °C / 0.2mmHg
• Flash Point: 196.3 °C
• Appearance: white to off-white powder
• Density: 1.195 g/cm³
• Vapor Pressure: 4.6Pa at 20℃
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: soluble in Tetrahydrofuran
• Water Solubility: 200ng/L at 20℃
• CAS DataBase Reference: 4,4'-Bis(chloromethyl)-1,1'-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-Bis(chloromethyl)-1,1'-biphenyl(1667-10-3)
• EPA Substance Registry System: 4,4'-Bis(chloromethyl)-1,1'-biphenyl(1667-10-3)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 1667-10-3(Hazardous Substances Data)

Usage

Chemical Properties

White to light brown solid

Flammability and Explosibility

Notclassified

Upstream product

• 50-00-0 formaldehyd 
• 92-52-4 biphenyl 
• 542-88-1 bis(2-chloromethyl)ether 
• 613-33-2 (4,4'-dimethyl-1,1'-biphenyl) 
• 787-70-2 4,4'-diphenic acid 
• 1667-12-5 4,4'-bis(hydroxymethyl)biphenyl 
• 75-15-0 carbon disulfide 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 7255-83-6 4,4’-bis(cyanomethyl)-1,1’biphenyl 
• 54050-02-1 biphenyl-4,4'-bis(methyltriphenylphosphonium chloride) 
• 55076-40-9 1,1'-[1,1'-biphenyl-4,4'-diylbis(methylene)]bis[piperidine] 
• 63946-23-6 4,4'-[biphenyl-4,4'-diylbis(methylene)]bis-morpholine 
• 613-33-2 (4,4'-dimethyl-1,1'-biphenyl) 
• 29041-31-4 1,2,5,6(1,4)-tetrabenzenacyclooctaphane 
• 1006377-79-2 1-((4'-((pyridin-3-yloxy)methyl)biphenyl-4-yl)methyl)pyridinium-3-olate 
• 886212-15-3 4,4'-bis(5-(trichlorostannyl)butyloxymethyl)biphenyl 
• 43012-19-7 [1,1'-biphenyl]-4,4'-dimethanethiol 
• 1268162-69-1 4,4'-bis(3-methylphenoxymethyl)-1,1'-biphenyl 
• 1283072-03-6 4,4'-bis((2-methyl-1H-imidazol-1-yl)methyl)-1,1'-biphenyl 

Relevant articles and documents

Synthesis, antimicrobial and antifungal activity of double quaternary ammonium salts of biphenyls

The synthetic methods for new 2-, 2,2′-, and 3-substituted 4,4′-bis(chloromethyl)biphenyls were developed. Quaternization of them with various amines resulted in a series of new double quaternary ammonium salts containing the biphenyl moiety. The majority of the obtained compounds have a pronounced antifungal and antibacterial activity against the Gram-positive bacteria.

Method for preparing biphenyl benzyl dichloride through photocatalytic chlorination

The invention discloses a method for preparing biphenyl benzyl dichloride through photocatalytic chlorination. The method comprises the following steps: adding 4,4'-dimethyl biphenyl, a solvent and acatalyst into a reaction kettle, and carrying out stirring dissolution; turning on an ultraviolet lamp, and starting to introduce chlorine from the bottom; after 5 hours, monitoring the reaction process by gas chromatography, stopping the chlorine introducing when the total content of high-chlorinated products such as trichlorocompounds, tetrachlorocompounds and the like on the chromatography reaches 3%, continuously stirring for a certain time to expel residual chlorine, and then heating to evaporate out most of the solvent to obtain a crude product; and in the same reaction kettle, cooling the obtained crude product to below 40 DEG C, adding a solvent for recrystallization, continuously heating until the solvent is refluxed, completely dissolving the crude product, carrying out cooling crystallizing under stirring, filtering, and drying to obtain a white refined product.

Catalysis preparation process for 4,4'-dichloro methyl biphenyl

The invention discloses a catalysis preparation process for 4,4'-dichloro methyl biphenyl. The catalysis preparation process comprises the steps: putting biphenyl, hydrochloric acid with the mass fraction of 27-37% and paraformaldehyde according to the weight ratio of 1:(3-4):(0.65-0.85) into a reactor, adding a solid catalyst, then adding an organic solvent, heating up to 50-80 DEG C, introducing HCl gas, carrying out a reaction for 10-20 hours, then filtering the reaction liquid to obtain the solid catalyst, allowing the liquid to stand to separate out an acid phase, washing an organic phase with water, crystallizing, and filtering to obtain a crude product, and recrystallizing the crude product to obtain the target product 4,4'-dichloro methyl biphenyl. The preparation process provided by the invention has high conversion rate; the solid catalyst can be repeatedly used, and the catalytic efficiency is not significantly reduced after the solid catalyst is repeatedly used for 40 times.