1-(3-Hydroxypropyl)-3-phenylurea

Base Information

Chemical Name:1-(3-Hydroxypropyl)-3-phenylurea
CAS No.:4974-07-6
Molecular Formula:C10H14N2O2
Molecular Weight:194.233
Hs Code.:
DSSTox Substance ID:DTXSID10198003
Nikkaji Number:J2.966.910D
Wikidata:Q83070766
ChEMBL ID:CHEMBL3463259

Synonyms:1-(3-Hydroxypropyl)-3-phenylurea;Urea, 1-(3-hydroxypropyl)-3-phenyl-;4974-07-6;CBDivE_014274;SCHEMBL3065011;CHEMBL3463259;DTXSID10198003;AKOS008056428;Z104685312

Suppliers and Price of 1-(3-Hydroxypropyl)-3-phenylurea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-(3-Hydroxypropyl)-3-phenylurea

Chemical Property:

Vapor Pressure:2.73E-05mmHg at 25°C
Boiling Point:343.3°C at 760 mmHg
Flash Point:161.4°C
Density:1.2g/cm³
XLogP3:0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:194.105527694
Heavy Atom Count:14
Complexity:168

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC(=O)NCCCO

Technology Process of 1-(3-Hydroxypropyl)-3-phenylurea

There total 4 articles about 1-(3-Hydroxypropyl)-3-phenylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 370-32-1
phenylcarbamic acid 2,2,2-trifluoroethyl ester

: 156-87-6
propan-1-ol-3-amine

: 4974-07-6
1-(3-hydroxypropyl)-3-phenylurea

Guidance literature:: In acetonitrile; at 100 ℃; for 4h;
DOI:10.1016/j.tet.2011.03.101

Reference yield: 82.0%

: 103-71-9
phenyl isocyanate

: 156-87-6
propan-1-ol-3-amine

: 4974-07-6
1-(3-hydroxypropyl)-3-phenylurea

Guidance literature:: In diethyl ether;
DOI:10.1023/A:1011385405611

Reference yield:

: 103-71-9
phenyl isocyanate

: 4974-07-6
1-(3-hydroxypropyl)-3-phenylurea

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / hexane; toluene / 4 h / Reflux

2: acetonitrile / 4 h / 100 °C

With triethylamine; In hexane; toluene; acetonitrile;
DOI:10.1016/j.tet.2011.03.101